Unfoldness of the denatured state of proteins determines urea: Methylamine counteraction in terms of Gibbs free energy of stabilization.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.03.236
Abstract: In many tissues and organisms, large amount of urea gets accumulated to maintain osmotic balance. To evade the threatening impact of urea, living organisms accumulate methylamines, a class of osmolytes, in proportion of 2:1 (urea:methylamine).… read more here.
Keywords: counteraction; urea methylamine; unfoldness denatured; perfect compensation ... See more keywords
Quantitative calorimetric evidences into counteraction mechanism of denaturing effect of guanidine hydrochloride by citrulline and betaine
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2020.114953
Abstract: Abstract Obtaining qualitative and quantitative insights into counteraction mechanism of deleterious effects of denaturants on proteins is crucial because of its fundamental impact on biological and industrial processes. In this work, we have employed a… read more here.
Keywords: counteraction; guanidine hydrochloride; counteraction mechanism;
Human IFITM3 restricts chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction
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DOI: 10.26508/lsa.202000909
Abstract: Endogenous and heterologpusly expressed human IFITM3 restricts early and late replication steps of chikungunya and Mayaro virus infection and is downregulated at the protein level in infected cells. Interferon-induced transmembrane (IFITM) proteins restrict membrane fusion… read more here.
Keywords: counteraction; mayaro virus; infection; virus infection ... See more keywords