Coupling Chlorin-Based Photosensitizers and Histone Deacetylase Inhibitors for Photodynamic Chemotherapy.
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DOI: 10.1021/acs.molpharmaceut.2c00170
Abstract: Photodynamic therapy combined with chemotherapy is a promising strategy to improve the antitumor efficacy. On the basis of coupling the chlorin-based photosensitizer pyropheophorbide a (Pyro) and histone deacetylase inhibitors (HDACis) to fabricate dual-mode antitumor molecules,… read more here.
Keywords: chlorin based; antitumor; deacetylase inhibitors; chemotherapy ... See more keywords