Construction of Bisindolines via Oxidative Coupling Cyclization.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b04037
Abstract: Herein, we report a general approach for the efficient construction of three-dimensional bisindolines via oxidative coupling cyclization in an intermolecular manner. This reaction is featured by its operational simplicity, metal-free conditions, lack of protecting group,… read more here.
Keywords: construction; cyclization; bisindolines via; oxidative coupling ... See more keywords
Palladium-Catalyzed Atroposelective Coupling-Cyclization of 2-Isocyanobenzamides to Construct Axially Chiral 2-Aryl- and 2,3-Diarylquinazolinones.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c00640
Abstract: A palladium-catalyzed imidoylative cycloamidation of N-alkyl-2-isocyanobenzamides with 2,6-disubstituted aryl iodides, affording unprecedented axially chiral 2-arylquinazolinones, has been developed with good yields and atroposelectivities. In this coupling-cyclization process, the biaryl linkage and the heteroaromatic ring are… read more here.
Keywords: palladium catalyzed; coupling cyclization; axially chiral; catalyzed atroposelective ... See more keywords
[Cp*RhCl2]2 Catalyzed Three-Component Coupling Cyclization of 2,3-Allenoic Acids with 2,3-Allenols in the Presence of Cu(OAc)2·H2O
Sign Up to like & getrecommendations! Published in 2023 at "Organic Chemistry Frontiers"
DOI: 10.1039/d3qo00608e
Abstract: Here we report a [Cp*RhCl2]2 catalyzed three-component coupling cyclization of 2,3-allenoic acids and 2,3-allenols in the presence of Cu(OAc)2.H2O affording furanone derivatives. The synthetic potentials have been demonstrated. The mechanism... read more here.
Keywords: coupling cyclization; rhcl2 catalyzed; cyclization allenoic; catalyzed three ... See more keywords