Synthesis of Pyrroles Through the CuH-Catalyzed Coupling of Enynes and Nitriles.
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DOI: 10.1021/jacs.0c03859
Abstract: Herein, we describe an efficient method to prepare polysubstituted pyrroles via a copper-hydride (CuH)-catalyzed enyne-nitrile coupling reaction. This protocol accommodates both aromatic and aliphatic substituents and a broad range of functional groups, providing a variety… read more here.
Keywords: cuh catalyzed; enynes nitriles; synthesis pyrroles; catalyzed coupling ... See more keywords