Palladium-Catalyzed Sonogashira Coupling of a Heterocyclic Phosphonium Salt with a Terminal Alkyne.
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DOI: 10.1021/acs.orglett.2c01800
Abstract: An efficient Sonogashira coupling of a heterocyclic phosphonium salt with a terminal alkyne via C-P bond cleavage was developed. The reactions proceeded smoothly in the presence of palladium catalyst, copper(I) iodide, and N,N-diisopropylethylamine (DIPEA) in… read more here.
Keywords: coupling heterocyclic; phosphonium salt; heterocyclic phosphonium; sonogashira coupling ... See more keywords