Alkyne Hydroheteroarylation: Enantioselective Coupling of Indoles and Alkynes via Rh-Hydride Catalysis.
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DOI: 10.1021/jacs.7b05893
Abstract: We report an enantioselective coupling between alkynes and indoles. A Rh-hydride catalyst isomerizes alkynes to generate a metal-allyl species that can be trapped with both aromatic and heteroaromatic nucleophiles. read more here.
Keywords: enantioselective coupling; indoles alkynes; hydroheteroarylation enantioselective; coupling indoles ... See more keywords
N-Iodosuccinimide-Mediated Oxidative Coupling of Indoles and Phenols: A Synthetic Study toward the Benzofuroindoline Moiety of Bipleiophylline
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DOI: 10.1055/s-0036-1592002
Abstract: We report our efforts to apply an N-iodosuccinimide-mediated dearomative oxidative coupling of indoles and phenols to benzofuroindoline-containing polycyclic scaffolds related to the natural product bipleiophylline. Suitable conditions from N-substituted indoles are developed and applied to… read more here.
Keywords: indoles phenols; iodosuccinimide mediated; coupling indoles; oxidative coupling ... See more keywords
TEMPO/CuI synergetic catalyzed oxidative cross-coupling of indoles with benzylamines: Synthesis of bis(indolyl)phenylmethanes
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DOI: 10.1080/00397911.2018.1459722
Abstract: ABSTRACT TEMPO/CuI was found to be an effective catalyst for the cross-coupling of indoles with benzylic amines affording the corresponding bis(indolyl)phenylmethanes under air atmosphere at room temperature in good to excellent yields. The efficiency, easy… read more here.
Keywords: tempo cui; bis indolyl; coupling indoles; indolyl phenylmethanes ... See more keywords