Asymmetric Coupling of β-Ketocarbonyls and Alkynes by Chiral Primary Amine/Rh Synergistic Catalysis.
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DOI: 10.1021/acs.orglett.1c04334
Abstract: We herein report a synergetic chiral primary amine and rhodium catalysis for asymmetric coupling of β-ketocarbonyls and alkynes. A series of β-ketocarbonyls could be applied to afford linear allylation products, bearing all-carbon quaternary centers in… read more here.
Keywords: asymmetric coupling; ketocarbonyls alkynes; ketocarbonyls; coupling ketocarbonyls ... See more keywords