Photo-induced coupling of tertiary amines with Ugi-derived dehydroalanines as a practical device in the synthesis to 2,4-diaminobutyric acid derivatives
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.151152
Abstract: Abstract An Ir-mediated photocatalytic coupling of tertiary amines with Ugi-dehydroalanines was developed as an entry to medicinally important 2,4-diaminobutyric acid derivatives. In the process the 2,4-diaminobutyric acid framework is assembled directly embedded into a peptoide… read more here.
Keywords: tertiary amines; diaminobutyric acid; acid derivatives; amines ugi ... See more keywords
Enabling the Cross-Coupling of Tertiary Organoboron Nucleophiles through Radical-Mediated Alkyl Transfer.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b06288
Abstract: The construction of quaternary centers is a common challenge in the synthesis of complex materials and natural products. Current cross-coupling strategies that can be generalized for setting these centers are sparse and, when known, are… read more here.
Keywords: cross; cross coupling; tertiary organoboron; enabling cross ... See more keywords