Structure and sequence-based computational approaches to allosteric signal transduction: application to electromechanical coupling in voltage-gated ion channels.
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DOI: 10.1016/j.jmb.2021.167095
Abstract: Allosteric signaling underlies the function of many biomolecules, including membrane proteins such as ion channels. Experimental methods have enabled specific quantitative insights into the coupling between the voltage sensing domain and the pore gate of… read more here.
Keywords: ion channels; gated ion; coupling voltage; ion ... See more keywords