Classification algorithm for high-dimensional protein markers in time-course data.
Sign Up to like & getrecommendations! Published in 2020 at "Statistics in medicine"
DOI: 10.1002/sim.8720
Abstract: Identification of biomarkers is an emerging area in oncology. In this article, we develop an efficient statistical procedure for the classification of protein markers according to their effect on cancer progression. A high-dimensional time-course dataset… read more here.
Keywords: high dimensional; time course; course data; protein markers ... See more keywords
Integrating transcriptomics and bulk time course data into a mathematical framework to describe and predict therapeutic resistance in cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Physical biology"
DOI: 10.1088/1478-3975/abb09c
Abstract: A significant challenge in the field of biomedicine is the development of methods to integrate the multitude of dispersed data sets into comprehensive frameworks to be used to generate optimal clinical decisions. Recent technological advances… read more here.
Keywords: single cell; bulk time; framework; time course ... See more keywords
Systematic analysis of alternative splicing in time course data using Spycone
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac846
Abstract: During disease progression or organism development, alternative splicing (AS) may lead to isoform switches (IS) that demonstrate similar temporal patterns and reflect the AS co-regulation of such genes. Tools for dynamic process analysis usually neglect… read more here.
Keywords: alternative splicing; analysis; time course; course data ... See more keywords