Dynamic Regulation of SARS-Cov-2 Binding and Cell Entry Mechanisms in Remodeled Human Ventricular Myocardium
Sign Up to like & getrecommendations! Published in 2020 at "JACC: Basic to Translational Science"
DOI: 10.1016/j.jacbts.2020.06.007
Abstract: SUMMARY Using serial analysis of myocardial gene expression employing endomyocardial biopsy starting material in a dilated cardiomyopathy cohort, we show that the SARS-CoV-2 cardiac myocyte receptor ACE2 is upregulated with remodeling and with reverse remodeling… read more here.
Keywords: cov binding; regulation sars; entry; sars cov ... See more keywords
Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies
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DOI: 10.1080/19420862.2021.1922134
Abstract: ABSTRACT Antibodies against coronavirus spike protein potently protect against infection and disease, but whether such protection can be extended to variant coronaviruses is unclear. This is exemplified by a set of iconic and well-characterized monoclonal… read more here.
Keywords: maturation; cov binding; antibody; potent sars ... See more keywords
SARS-CoV-2 Binding and Neutralization Properties of Peptides Derived from N-Terminus of Human ACE2
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DOI: 10.3390/ijms24098269
Abstract: The binding properties of synthetic and recombinant peptides derived from N-terminal part of ACE2, the main receptor for SARS-CoV-2, were evaluated. Additionally, the ability of these peptides to prevent virus entry in vitro was addressed… read more here.
Keywords: binding neutralization; cov binding; properties peptides; peptides derived ... See more keywords
Modelling SARS-CoV-2 Binding Antibody Waning 8 Months after BNT162b2 Vaccination
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DOI: 10.3390/vaccines10020285
Abstract: Several lines of evidence suggest that binding SARS-CoV-2 antibodies such as anti-SARS-CoV-2 RBD IgG (anti-RBD) and neutralising antibodies (NA) are correlates of protection against SARS-CoV-2, and the correlation of anti-RBD and NA is very high.… read more here.
Keywords: cov binding; vaccination; modelling sars; anti rbd ... See more keywords