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   Articles with "cov evolution" as a keyword



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Insights into SARS-CoV-2 evolution, potential antivirals, and vaccines

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recommendations! Published in 2021 at "Virology"

DOI: 10.1016/j.virol.2021.02.007

Abstract: SARS-CoV-2 is a novel coronavirus, spread among humans, and to date, more than 100 million of laboratory-confirmed cases have been reported worldwide. The virus demonstrates 96% similarity to a coronavirus from a horseshoe bat and… read more here.

Keywords: evolution potential; potential antivirals; cov evolution; insights sars ... See more keywords
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SARS-CoV-2 evolution influences GBP and IFITM sensitivity

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recommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2212577120

Abstract: Significance GBPs and IFITMs are potent innate immune restriction factors that can inhibit viral infectivity. Specifically, GBPs perturb furin-mediated processing of viral envelope proteins, targeting viruses that rely on proteolytic processing for optimal infectivity. Here,… read more here.

Keywords: gbp ifitm; influences gbp; evolution influences; cov evolution ... See more keywords
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The interplay of SARS-CoV-2 evolution and constraints imposed by the structure and functionality of its proteins

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recommendations! Published in 2021 at "PLoS Computational Biology"

DOI: 10.1371/journal.pcbi.1009147

Abstract: The unprecedented pace of the sequencing of the SARS-CoV-2 virus genomes provides us with unique information about the genetic changes in a single pathogen during ongoing pandemic. By the analysis of close to 200,000 genomes… read more here.

Keywords: evolution constraints; imposed structure; constraints imposed; cov evolution ... See more keywords
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SARS-CoV-2: Evolution and Emergence of New Viral Variants

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recommendations! Published in 2022 at "Viruses"

DOI: 10.3390/v14040653

Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent responsible for the coronavirus disease 2019 (COVID-19). The high rate of mutation of this virus is associated with a quick emergence of new… read more here.

Keywords: new viral; emergence new; viral variants; cov evolution ... See more keywords