Detection of viral SARS‐CoV‐2 genomes and histopathological changes in endomyocardial biopsies
Sign Up to like & getrecommendations! Published in 2020 at "ESC Heart Failure"
DOI: 10.1002/ehf2.12805
Abstract: Since December 2019, the novel coronavirus SARS‐CoV‐2 has spread rapidly throughout China and keeps the world in suspense. Cardiovascular complications with myocarditis and embolism due to COVID‐19 have been reported. SARS‐CoV‐2 genome detection in the… read more here.
Keywords: detection viral; genomes histopathological; histopathological changes; cov genomes ... See more keywords
Genome-wide analysis of Indian SARS-CoV-2 genomes to identify T-cell and B-cell epitopes from conserved regions based on immunogenicity and antigenicity
Sign Up to like & getrecommendations! Published in 2021 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2020.107276
Abstract: SARS-CoV-2 has a high transmission rate and shows frequent mutations, thus making vaccine development an arduous task. However, researchers around the globe are working hard to find a solution e.g. synthetic vaccine. Here, we have… read more here.
Keywords: consensus conserved; cell epitopes; cov genomes; sars cov ... See more keywords
Immunogenicity and antigenicity based T-cell and B-cell epitopes identification from conserved regions of 10664 SARS-CoV-2 genomes
Sign Up to like & getrecommendations! Published in 2021 at "Infection, Genetics and Evolution"
DOI: 10.1016/j.meegid.2021.104823
Abstract: The surge of SARS-CoV-2 has created a wave of pandemic around the globe due to its high transmission rate. To contain this virus, researchers are working around the clock for a solution in the form… read more here.
Keywords: cell cell; cell epitopes; cov genomes; sars cov ... See more keywords
Characterization of the SARS-CoV-2 genomes in Egypt in first and second waves of infection
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DOI: 10.1038/s41598-021-99014-4
Abstract: At Wuhan, in December 2019, the SRAS-CoV-2 outbreak was detected and it has been the pandemic worldwide. This study aims to investigate the mutations in sequence of the SARS-CoV-2 genome and characterize the mutation patterns… read more here.
Keywords: genomes egypt; infection; cov genomes; characterization sars ... See more keywords
The Slowing Rate of CpG Depletion in SARS-CoV-2 Genomes Is Consistent with Adaptations to the Human Host
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msac029
Abstract: Abstract Depletion of CpG dinucleotides in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) genomes has been linked to virus evolution, host-switching, virus replication, and innate immune responses. Temporal variations, if any, in the rate of CpG… read more here.
Keywords: cpg depletion; depletion; rate; cov genomes ... See more keywords
Large scale genomic analysis of 3067 SARS-CoV-2 genomes reveals a clonal geo-distribution and a rich genetic variations of hotspots mutations
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0240345
Abstract: In late December 2019, an emerging viral infection COVID-19 was identified in Wuhan, China, and became a global pandemic. Characterization of the genetic variants of SARS-CoV-2 is crucial in following and evaluating it spread across… read more here.
Keywords: large scale; analysis; cov genomes; scale genomic ... See more keywords
Genomic Variations in SARS-CoV-2 Genomes From Gujarat: Underlying Role of Variants in Disease Epidemiology
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.586569
Abstract: Humanity has seen numerous pandemics during its course of evolution. The list includes several incidents from the past, such as measles, Ebola, severe acute respiratory syndrome (SARS), and Middle East respiratory syndrome (MERS), etc. The… read more here.
Keywords: patients gujarat; cov genomes; epidemiology; role ... See more keywords
A Timeframe for SARS-CoV-2 Genomes: A Proof of Concept for Postmortem Interval Estimations
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232112899
Abstract: Establishing the timeframe when a particular virus was circulating in a population could be useful in several areas of biomedical research, including microbiology and legal medicine. Using simulations, we demonstrate that the circulation timeframe of… read more here.
Keywords: proof concept; postmortem; timeframe sars; microbiology ... See more keywords
Evaluating Data Sharing of SARS-CoV-2 Genomes for Molecular Epidemiology across the COVID-19 Pandemic
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15020560
Abstract: Following the emergence of COVID-19 in December 2019, caused by the coronavirus SARS-CoV-2, the disease spread dramatically worldwide. The use of genomics to trace the dissemination of the virus and the identification of novel variants… read more here.
Keywords: data sharing; sharing sars; evaluating data; cov genomes ... See more keywords