Phillyrin (KD-1) exerts anti-viral and anti-inflammatory activities against novel coronavirus (SARS-CoV-2) and human coronavirus 229E (HCoV-229E) by suppressing the nuclear factor kappa B (NF-κB) signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "Phytomedicine"
DOI: 10.1016/j.phymed.2020.153296
Abstract: Abstract Background : Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has extensively and rapidly spread in the world, causing an outbreak of acute infectious pneumonia. However, no specific antiviral drugs or vaccines can be used.… read more here.
Keywords: anti inflammatory; coronavirus; hcov 229e; sars cov ... See more keywords
Exploring the Spike-hACE 2 Residue–Residue Interaction in Human Coronaviruses SARS-CoV-2, SARS-CoV, and HCoV-NL63
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Chemical Information and Modeling"
DOI: 10.1021/acs.jcim.1c01544
Abstract: Coronaviruses (CoVs) have been responsible for three major outbreaks since the beginning of the 21st century, and the emergence of the recent COVID-19 pandemic has resulted in considerable efforts to design new therapies against coronaviruses.… read more here.
Keywords: cov hcov; interaction; hcov nl63; hace ... See more keywords
Antiviral Peptides Delivered by Chitosan-Based Nanoparticles to Neutralize SARS-CoV-2 and HCoV-OC43
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DOI: 10.3390/pharmaceutics15061621
Abstract: The COVID-19 pandemic has made it clear that there is a crucial need for the design and development of antiviral agents that can efficiently reduce the fatality rate caused by infectious diseases. The fact that… read more here.
Keywords: cov hcov; chitosan based; antiviral peptides; based nanoparticles ... See more keywords