Omicron N501Y mutation among SARS-CoV-2 lineages: In silico analysis of potent binding to tyrosine kinase and hypothetical repurposed medicine
Sign Up to like & getrecommendations! Published in 2021 at "Travel Medicine and Infectious Disease"
DOI: 10.1016/j.tmaid.2021.102242
Abstract: Variants of SARS-CoV-2 lineages including the most recently circulated Omicron, and previous pandemic B.1.351, B.1.1.7, which have been public concerns, contain a N501Y mutation located in the spike receptor binding domain. However, the potential interactions… read more here.
Keywords: analysis; n501y mutation; sars cov; medicine ... See more keywords
Tracking cryptic SARS-CoV-2 lineages detected in NYC wastewater
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DOI: 10.1038/s41467-022-28246-3
Abstract: Tracking SARS-CoV-2 genetic diversity is strongly indicated because diversifying selection may lead to the emergence of novel variants resistant to naturally acquired or vaccine-induced immunity. To monitor New York City (NYC) for the presence of… read more here.
Keywords: wastewater; sars cov; cryptic sars; cov lineages ... See more keywords
Multiple expansions of globally uncommon SARS-CoV-2 lineages in Nigeria
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-022-28317-5
Abstract: Disparities in SARS-CoV-2 genomic surveillance have limited our understanding of the viral population dynamics and may delay identification of globally important variants. Despite being the most populated country in Africa, Nigeria has remained critically under… read more here.
Keywords: genomic surveillance; sars cov; globally uncommon; lineages nigeria ... See more keywords
Highly Sensitive Lineage Discrimination of SARS-CoV-2 Variants through Allele-Specific Probe PCR
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.02283-21
Abstract: Tools to detect SARS-CoV-2 variants of concern and track the ongoing evolution of the virus are necessary to support public health efforts and the design and evaluation of novel COVID-19 therapeutics and vaccines. Although next-generation… read more here.
Keywords: cov variants; viral loads; asp pcr; pcr ... See more keywords
Contrasting Distribution of SARS-CoV-2 Lineages across Multiple Rounds of Pandemic Waves in West Bengal, the Gateway of East and North-East States of India
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00914-22
Abstract: Multiple waves of infection were observed in many states in India during the coronavirus disease 2019 (COVID19) pandemic. Fine-scale evolution of major SARS-CoV-2 lineages and sublineages during four wave-window categories: Pre-Wave 1, Wave 1, Pre-Wave… read more here.
Keywords: states india; west bengal; wave wave; pre wave ... See more keywords
Genomic Surveillance of SARS-CoV-2 Lineages Indicates Early Circulation of P.1 (Gamma) Variant of Concern in Southern Brazil
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.01511-21
Abstract: The SARS-CoV-2 P.1 lineage is associated with increased transmissibility and/or immune evasion and presents a dynamic evolution in Brazil. The significance of our research relies in the fact that we evaluated the SARS-CoV-2 lineages circulating… read more here.
Keywords: lineage; cov lineages; southern brazil; sars cov ... See more keywords
Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2.
Sign Up to like & getrecommendations! Published in 2021 at "Wellcome open research"
DOI: 10.12688/wellcomeopenres.16661.1
Abstract: Late in 2020, two genetically-distinct clusters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mutations of biological concern were reported, one in the United Kingdom and one in South Africa. Using a combination of… read more here.
Keywords: tracking international; cov lineages; international spread; lineages 351 ... See more keywords
OmniSARS2: A Highly Sensitive and Specific RT-qPCR-Based COVID-19 Diagnostic Method Designed to Withstand SARS-CoV-2 Lineage Evolution
Sign Up to like & getrecommendations! Published in 2021 at "Biomedicines"
DOI: 10.3390/biomedicines9101314
Abstract: Extensive transmission of SARS-CoV-2 during the COVID-19 pandemic allowed the generation of thousands of mutations within its genome. While several of these become rare, others largely increase in prevalence, potentially jeopardizing the sensitivity of PCR-based… read more here.
Keywords: cov lineages; method; lineage evolution; sars cov ... See more keywords
Phylodynamic Dispersal of SARS-CoV-2 Lineages Circulating across Polish–German Border Provinces
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DOI: 10.3390/v14050884
Abstract: Introduction: The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has evolved into a worldwide outbreak, with significant molecular evolution over time. Large-scale phylodynamic studies allow to map the virus spread and inform preventive strategies.… read more here.
Keywords: phylodynamic dispersal; dispersal sars; border provinces; cov lineages ... See more keywords
Omicron Waves in Argentina: Dynamics of SARS-CoV-2 Lineages BA.1, BA.2 and the Emerging BA.2.12.1 and BA.4/BA.5
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15020312
Abstract: The COVID-19 pandemic has lately been driven by Omicron. This work aimed to study the dynamics of SARS-CoV-2 Omicron lineages during the third and fourth waves of COVID-19 in Argentina. Molecular surveillance was performed on… read more here.
Keywords: dynamics sars; waves argentina; argentina dynamics; cov lineages ... See more keywords
SARSMutOnto: An Ontology for SARS-CoV-2 Lineages and Mutations
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15020505
Abstract: Mutations allow viruses to continuously evolve by changing their genetic code to adapt to the hosts they infect. It is an adaptive and evolutionary mechanism that helps viruses acquire characteristics favoring their survival and propagation.… read more here.
Keywords: sarsmutonto ontology; ontology; ontology sars; lineages mutations ... See more keywords