SARS-CoV-2, SARS-CoV and MERS-CoV encode circular RNAs of spliceosome-independent origin.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medical virology"
DOI: 10.1002/jmv.27734
Abstract: Circular RNAs (circRNAs) are a newly recognized component of the transcriptome with critical roles in autoimmune diseases and viral pathogenesis. To address the importance of circRNA in RNA viral transcriptome, we systematically identified and characterized… read more here.
Keywords: cov mers; sars cov; cov sars; spliceosome independent ... See more keywords
A Comprehensive Review of Animal Models for Coronaviruses: SARS-CoV-2, SARS-CoV, and MERS-CoV
Sign Up to like & getrecommendations! Published in 2020 at "Virologica Sinica"
DOI: 10.1007/s12250-020-00252-z
Abstract: The recent outbreak of coronavirus disease (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has already affected a large population of the world. SARS-CoV-2 belongs to the same family of severe acute… read more here.
Keywords: cov mers; cov sars; animal models; coronavirus ... See more keywords
SARS-CoV, MERS-CoV, and 2019-nCoV viruses: an overview of origin, evolution, and genetic variations
Sign Up to like & getrecommendations! Published in 2020 at "VirusDisease"
DOI: 10.1007/s13337-020-00632-9
Abstract: Coronaviruses are single stranded RNA viruses usually present in bats (reservoir hosts), and are generally lethal, highly transmissible, and pathogenic viruses causing sever morbidity and mortality rates in human. Several animals including civets, camels, etc.… read more here.
Keywords: cov mers; 2019 ncov; cov 2019; epidemiology ... See more keywords
SARS-CoV, MERS-CoV and SARS-CoV-2: A Diagnostic Challenge
Sign Up to like & getrecommendations! Published in 2021 at "Measurement"
DOI: 10.1016/j.measurement.2020.108335
Abstract: The highly pathogenic MERS-CoV, SARS-CoV and SARS-CoV-2 cause acute respiratory syndrome and are often fatal. These new viruses pose major problems to global health in general and primarily to infection control and public health services.… read more here.
Keywords: cov mers; cov sars; cov diagnostic; sars cov ... See more keywords
SARS-CoV, MERS-CoV and now the 2019-novel CoV: Have we investigated enough about coronaviruses? – A bibliometric analysis☆
Sign Up to like & getrecommendations! Published in 2020 at "Travel Medicine and Infectious Disease"
DOI: 10.1016/j.tmaid.2020.101566
Abstract: Here we discuss the potential of targeting Dihydroorotate dehydrogenase enzyme to heltreat Covid 19 Next, we present a very large scale of docking analysis using 7900 drug candidates and 20 Dihydroorotate dehydrogenase structures Our findings… read more here.
Keywords: cov mers; analysis; 2019 novel; cov 2019 ... See more keywords
TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models after Coronavirus Infection
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Virology"
DOI: 10.1128/jvi.01815-18
Abstract: Broad-spectrum antiviral drugs against highly pathogenic coronaviruses and other emerging viruses are desirable to enable a rapid response to pandemic threats. Transmembrane protease serine type 2 (TMPRSS2), a protease belonging to the type II transmembrane… read more here.
Keywords: cov mers; immunopathology; mers cov; infection ... See more keywords
A Review of SARS-CoV2: Compared With SARS-CoV and MERS-CoV
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.628370
Abstract: The outbreak of coronavirus disease 2019 (COVID-19) has been spreading rapidly in China and the Chinese government took a series of policies to control the epidemic. Studies found that severe COVID-19 is characterized by pneumonia,… read more here.
Keywords: review; cov mers; sars cov; sars cov2 ... See more keywords
Coronavirus Inhibitors Targeting nsp16
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28030988
Abstract: During the past three decades, humans have been confronted with different new coronavirus outbreaks. Since the end of the year 2019, COVID-19 threatens the world as a rapidly spreading infectious disease. For this work, we… read more here.
Keywords: inhibitors targeting; cov mers; coronavirus inhibitors; cov sars ... See more keywords
Fluoroquinolone Antibiotics Exhibit Low Antiviral Activity against SARS-CoV-2 and MERS-CoV
Sign Up to like & getrecommendations! Published in 2020 at "Viruses"
DOI: 10.3390/v13010008
Abstract: Repurposing FDA-approved drugs that treat respiratory infections caused by coronaviruses, such as SARS-CoV-2 and MERS-CoV, could quickly provide much needed antiviral therapies. In the current study, the potency and cellular toxicity of four fluoroquinolones (enoxacin,… read more here.
Keywords: cov mers; vero cells; toxicity; sars cov ... See more keywords
Immune Responses in SARS-CoV-2, SARS-CoV, and MERS-CoV Infections: A Comparative Review
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Preventive Medicine"
DOI: 10.4103/ijpvm.ijpvm_429_20
Abstract: Coronavirus, discovered in the 1960s, is able to infect human hosts and causes mild to serious respiratory problems. In the last two decades, the severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus… read more here.
Keywords: cov mers; immune responses; coronavirus; mers cov ... See more keywords