Effectiveness of a third dose of BNT162b2 anti-SARS-CoV-2 mRNA vaccine over a 6-month follow-up period in allogenic hematopoietic stem cells recipients.
Sign Up to like & getrecommendations! Published in 2022 at "Hematological oncology"
DOI: 10.1002/hon.3006
Abstract: This study reports the effectiveness of three injections of BNT162b2 anti-SARS-CoV-2 mRNA vaccine in 141 Allo-HSCT recipients with a median follow-up of 6 months post-third shot. We demonstrate a long-term high protection of Allo-HSCT recipients… read more here.
Keywords: cov mrna; anti sars; bnt162b2 anti; mrna vaccine ... See more keywords
Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals
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DOI: 10.1016/j.cell.2022.01.027
Abstract: Vaccine-mediated immunity often relies on the generation of protective antibodies and memory B cells, which commonly stem from germinal center (GC) reactions. An in-depth comparison of the GC responses elicited by SARS-CoV-2 mRNA vaccines in… read more here.
Keywords: mrna vaccines; sars cov; immunocompromised individuals; germinal center ... See more keywords
A short discussion about the SARS-CoV-2 mRNA-1273 vaccine
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Infectious Diseases"
DOI: 10.1016/j.ijid.2021.01.048
Abstract: The COVID-19 global pandemic has prompted accelerated vaccine development efforts. This perspective discusses the importance of SARS-CoV-2 vaccine candidates’ recruitment of cellular T-cell immunity and encourages industry to increasingly investigate and publish parameters related to… read more here.
Keywords: vaccine; cov mrna; mrna 1273; short discussion ... See more keywords
SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation
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DOI: 10.1016/j.immuni.2020.11.009
Abstract: The deployment of effective vaccines against SARS-CoV-2 is critical to eradicate the COVID-19 pandemic. Many licensed vaccines confer protection by inducing long-lived plasma cells (LLPC) and memory B cells (MBC), cell types canonically generated during… read more here.
Keywords: germinal center; cov mrna; mrna vaccines; neutralizing antibody ... See more keywords
Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy.
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DOI: 10.1038/s41591-021-01507-2
Abstract: SARS-CoV-2 messenger RNA vaccination in healthy individuals generates immune protection against COVID-19. However, little is known about SARS-CoV-2 mRNA vaccine-induced responses in immunosuppressed patients. We investigated induction of antigen-specific antibody, B cell and T cell… read more here.
Keywords: cell responses; cov mrna; vaccination; anti cd20 ... See more keywords
Systemic Vasculitis Following SARS-CoV-2 mRNA Vaccination Demonstrated on FDG PET/CT
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DOI: 10.1097/rlu.0000000000004115
Abstract: Abstract Causality regarding adverse events following SARS-CoV-2 mRNA vaccine is undetermined for vasculitis. Herein, we report the case of an 80-year-old man who presented with a persistent high fever of 7 days' duration that began… read more here.
Keywords: cov mrna; systemic vasculitis; fdg pet; following sars ... See more keywords
Immunogenicity and Reactogenicity After SARS-CoV-2 mRNA Vaccination in Kidney Transplant Recipients Taking Belatacept
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DOI: 10.1097/tp.0000000000003824
Abstract: Background. Belatacept may impair humoral immunity, impacting the effectiveness of SARS-CoV-2 mRNA vaccines in transplant recipients. We investigated immunogenicity after SARS-CoV-2 mRNA vaccines in kidney transplant recipients who are and are not taking belatacept. Methods.… read more here.
Keywords: cov mrna; kidney transplant; transplant recipients; taking belatacept ... See more keywords
Strong antibody response after a first dose of a SARS‐CoV‐2 mRNA‐based vaccine in kidney transplant recipients with a previous history of COVID‐19
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DOI: 10.1111/ajt.16764
Abstract: A recent study demonstrated that a single dose of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA-based vaccine is sufficient to mount a robust immunological response in immunocompetent subjects with a previous history of… read more here.
Keywords: based vaccine; mrna based; cov mrna; covid ... See more keywords
mTOR inhibitors, mycophenolates, and other immunosuppression regimens on antibody response to SARS-CoV-2 mRNA vaccines in solid organ transplant recipients
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Transplantation"
DOI: 10.1111/ajt.17158
Abstract: A recent study concluded that SARS‐CoV‐2 mRNA vaccine responses were improved among transplant patients taking mTOR inhibitors (mTORi). This could have profound implications for vaccine strategies in transplant patients; however, limitations in the study design… read more here.
Keywords: mtor inhibitors; antibody response; cov mrna; mmf ... See more keywords
SARS‐CoV‐2 mRNA vaccine‐associated fixed drug eruption
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.17390
Abstract: A 26-year-old, healthy, female nurse on no regular medication, developed a mildly pruritic, erythematous, annular patch with faint, central clearing on her left shoulder (Figure 1a). The patient had received the first dose of the… read more here.
Keywords: mrna vaccine; cov mrna; associated fixed; sars cov ... See more keywords
Severe Autoimmune Hemolytic Anemia Following Receipt of SARS-CoV-2 mRNA Vaccine.
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DOI: 10.1111/trf.16672
Abstract: Large clinical trials have demonstrated the overall safety of vaccines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, reports have emerged of autoimmune phenomena, including vaccine-associated myocarditis,1 immune thrombocytopenia,2 and immune thrombotic thrombocytopenia.3 4… read more here.
Keywords: autoimmune hemolytic; vaccine; mrna vaccine; cov mrna ... See more keywords