Articles with "cov mutations" as a keyword



SARS-CoV-2 mutations acquired in mink reduce antibody-mediated neutralization

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Published in 2021 at "Cell Reports"

DOI: 10.1016/j.celrep.2021.109017

Abstract: Transmission of SARS-CoV-2 from humans to farmed mink was observed in Europe and the US. In the infected animals viral variants arose that harbored mutations in the spike (S) protein, the target of neutralizing antibodies,… read more here.

Keywords: mink; antibody; cov mutations; neutralization ... See more keywords
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A one-step real-time RT-PCR assay for simultaneous typing of SARS-CoV-2 mutations associated with the E484K and N501Y spike protein amino-acid substitutions

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Published in 2021 at "Journal of Virological Methods"

DOI: 10.1016/j.jviromet.2021.114242

Abstract: The emergence of SARS-CoV-2 mutations resulting in the S protein amino-acid substitutions N501Y and E484K, which have been associated with enhanced transmissibility and immune escape, respectively, necessitates immediate actions, for which their rapid identification is… read more here.

Keywords: amino acid; cov mutations; protein amino; sars cov ... See more keywords

The human microbiota is a beneficial reservoir for SARS-CoV-2 mutations

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Published in 2024 at "mBio"

DOI: 10.1128/mbio.03187-23

Abstract: ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutations are rapidly emerging. In particular, beneficial mutations in the spike (S) protein, which can either make a person more infectious or enable immunological escape, are providing… read more here.

Keywords: sars cov; evolution; human microbiota; advantageous mutations ... See more keywords

The evaluation of SARS-CoV-2 mutations at the early stage of the pandemic in Istanbul population

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Published in 2024 at "Annals of Clinical Microbiology and Antimicrobials"

DOI: 10.1186/s12941-024-00750-y

Abstract: Determination of SARS-CoV-2 variant is significant to prevent the spreads of COVID-19 disease. We aimed to evaluate the variants of SARS-CoV-2 rate in positive patients in Kanuni Sultan Suleyman Training and Research Hospital (KSS-TRH), Istanbul,… read more here.

Keywords: sars cov; e484k; variant; cov mutations ... See more keywords

SARS-COV-2 mutations in North Rift, Kenya

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Published in 2025 at "PLOS One"

DOI: 10.1371/journal.pone.0325133

Abstract: The rise of new SARS-CoV-2 mutations brought challenges and progress in the global fight against COVID-19. Mutations in spike and accessory genes affect transmission, vaccine efficacy, treatments, testing, and public health strategies. Monitoring emerging variants… read more here.

Keywords: sars cov; north rift; rift kenya; cov mutations ... See more keywords

RT-qPCR Assays for Rapid Detection of the N501Y, 69-70del, K417N, and E484K SARS-CoV-2 Mutations: A Screening Strategy to Identify Variants With Clinical Impact

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Published in 2021 at "Frontiers in Cellular and Infection Microbiology"

DOI: 10.3389/fcimb.2021.672562

Abstract: Background Several variants of the SARS-CoV-2 have been documented globally during the current COVID-19 pandemic. The N501Y, 69-70del, K417N, and E484K SARS-CoV-2 mutations have been documented among the most relevant due to their potential pathogenic… read more here.

Keywords: n501y 70del; cov mutations; 70del k417n; qpcr assays ... See more keywords

Novel Lateral Flow-Based Assay for Simple and Visual Detection of SARS-CoV-2 Mutations

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Published in 2022 at "Frontiers in Cellular and Infection Microbiology"

DOI: 10.3389/fcimb.2022.902914

Abstract: Identification of the main SARS-CoV-2 variants in real time is of interest to control the virus and to rapidly devise appropriate public health responses. The RT-qPCR is currently considered to be the reference method to… read more here.

Keywords: performance; lateral flow; cov mutations; visual detection ... See more keywords

SARS-CoV-2 Mutations and Their Impact on Diagnostics, Therapeutics and Vaccines

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Published in 2022 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2022.815389

Abstract: With the high rate of COVID-19 infections worldwide, the emergence of SARS-CoV-2 variants was inevitable. Several mutations have been identified in the SARS-CoV-2 genome, with the spike protein as one of the mutational hot spots.… read more here.

Keywords: mutations impact; diagnostics therapeutics; therapeutics vaccines; cov mutations ... See more keywords

Unraveling the Dynamics of SARS-CoV-2 Mutations: Insights from Surface Plasmon Resonance Biosensor Kinetics

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Published in 2024 at "Biosensors"

DOI: 10.3390/bios14020099

Abstract: Surface Plasmon Resonance (SPR) technology is known to be a powerful tool for studying biomolecular interactions because it offers real-time and label-free multiparameter analysis with high sensitivity. This article summarizes the results that have been… read more here.

Keywords: sars cov; cov mutations; unraveling dynamics; plasmon resonance ... See more keywords