Elucidation of interactions regulating conformational stability and dynamics of SARS-CoV-2 S-protein
Sign Up to like & getrecommendations! Published in 2021 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2021.01.012
Abstract: Ongoing COVID-19 pandemic caused by new coronavirus, SARS-CoV-2, calls for urgent developments of vaccines and antiviral drugs. The spike protein of SARS-CoV-2 (S-protein), which consists of trimeric polypeptide chains with glycosylated residues on the surface,… read more here.
Keywords: cov protein; sars cov; stability; conformational transitions ... See more keywords
Molecular characterization of interactions between the D614G variant of SARS-CoV-2 S-protein and neutralizing antibodies: A computational approach
Sign Up to like & getrecommendations! Published in 2021 at "Infection, Genetics and Evolution"
DOI: 10.1016/j.meegid.2021.104815
Abstract: The D614G variant of SARS-CoV-2 S-protein emerged in early 2020 and quickly became the dominant circulating strain in Europe and its environs. The variant was characterized by the higher viral load, which is not associated with… read more here.
Keywords: protein neutralizing; cov protein; variant sars; neutralizing antibodies ... See more keywords
Human Amylin in the Presence of SARS-COV-2 Protein Fragments.
Sign Up to like & getrecommendations! Published in 2023 at "ACS omega"
DOI: 10.1021/acsomega.3c00621
Abstract: COVID-19 can lead to the onset of type-II diabetes, which is associated with the aggregation of islet amyloid polypeptides, also called amylin. Using molecular dynamics simulations, we investigate how the equilibrium between amylin monomers in… read more here.
Keywords: cov protein; protein fragments; presence sars; sars cov ... See more keywords
Antimicrobial peptide DP7 with potential activity against SARS coronavirus infections
Sign Up to like & getrecommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-021-00551-1
Abstract: Dear Editor, The outbreak of the SARS-CoV-2 epidemic once again demonstrates that RNA viruses, through mutations, genetic recombination and cross-species transmission, can pose a serious threat to the health of people worldwide. Even after the… read more here.
Keywords: dp7; cov protein; coronavirus; sars cov ... See more keywords
A detailed study of ion transport through the SARS-CoV-2 E protein ion channel.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr01385a
Abstract: The envelope (E) protein encoded in the genome of an RNA virus is crucial for the replication, budding and pathophysiology of the virus. In the light of the ongoing pandemic, we explored similarities/differences between SARS-CoV-1… read more here.
Keywords: protein ion; cov protein; sars cov; ion transport ... See more keywords
The Role of the SARS-CoV-2 S-Protein Glycosylation in the Interaction of SARS-CoV-2/ACE2 and Immunological Responses.
Sign Up to like & getrecommendations! Published in 2021 at "Viral immunology"
DOI: 10.1089/vim.2020.0174
Abstract: The current pandemic is caused by the coronavirus disease 2019 (COVID-19), which is, in turn, induced by a novel coronavirus (SARS-CoV-2) that triggers an acute respiratory disease. In recent years, the emergence of SARS-CoV-2 is… read more here.
Keywords: cov ace2; protein glycosylation; cov protein; coronavirus ... See more keywords
Identification and functional analysis of the SARS-COV-2 nucleocapsid protein
Sign Up to like & getrecommendations! Published in 2021 at "BMC Microbiology"
DOI: 10.1186/s12866-021-02107-3
Abstract: Background A severe form of pneumonia, named coronavirus disease 2019 (COVID-19) by the World Health Organization is widespread on the whole world. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was proved to be the… read more here.
Keywords: protein; cov nucleocapsid; analysis sars; cov protein ... See more keywords
Epitope Profiling Reveals the Critical Antigenic Determinants in SARS-CoV-2 RBD-Based Antigen
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.707977
Abstract: The ongoing COVID-19 pandemic caused by SARS-CoV-2 is a huge public health crisis for the globe. The receptor-binding domain (RBD) of SARS-CoV-2 spike (S) protein plays a vital role in viral infection and serves as… read more here.
Keywords: rbd based; cov protein; antibody response; sars cov ... See more keywords
The Molecular Basis of the Effect of Temperature on the Structure and Function of SARS-CoV-2 Spike Protein
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.794960
Abstract: The remarkable rise of the current COVID-19 pandemic to every part of the globe has raised key concerns for the current public healthcare system. The spike (S) protein of SARS-CoV-2 shows an important part in… read more here.
Keywords: structure function; temperature; spike protein; sars cov ... See more keywords
Plant Source Derived Compound Exhibited In Silico Inhibition of Membrane Glycoprotein In SARS-CoV-2: Paving the Way to Discover a New Class of Compound For Treatment of COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.805344
Abstract: SARS-CoV-2 is the virus responsible for causing COVID-19 disease in humans, creating the recent pandemic across the world, where lower production of Type I Interferon (IFN-I) is associated with the deadly form of the disease.… read more here.
Keywords: cov protein; compound; way; membrane ... See more keywords
Measurements of Anti-SARS-CoV-2 Antibody Levels after Vaccination Using a SH-SAW Biosensor
Sign Up to like & getrecommendations! Published in 2022 at "Biosensors"
DOI: 10.3390/bios12080599
Abstract: To prevent the COVID-19 pandemic that threatens human health, vaccination has become a useful and necessary tool in the response to the pandemic. The vaccine not only induces antibodies in the body, but may also… read more here.
Keywords: cov protein; vaccination; saw biosensor; anti sars ... See more keywords