Effects of simeprevir on the replication of SARS-CoV-2 in vitro and in transgenic hACE2 mice
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Antimicrobial Agents"
DOI: 10.1016/j.ijantimicag.2021.106499
Abstract: In a bid to contain the current COVID-19 (coronavirus disease 2019) pandemic, various countermeasures have been applied. To date, however, there is a lack of an effective drug for the treatment of COVID-19. Through molecular… read more here.
Keywords: hace2; sars cov; effects simeprevir; transgenic hace2 ... See more keywords
Lactoferrin Against SARS-CoV-2: In Vitro and In Silico Evidences
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DOI: 10.3389/fphar.2021.666600
Abstract: Lactoferrin (Lf) is a cationic glycoprotein synthetized by exocrine glands and is present in all human secretions. It is also secreted by neutrophils in infection and inflammation sites. This glycoprotein possesses antimicrobial activity due to… read more here.
Keywords: cov vitro; infection; vitro silico; sars cov ... See more keywords
Aurasperone A Inhibits SARS CoV-2 In Vitro: An Integrated In Vitro and In Silico Study
Sign Up to like & getrecommendations! Published in 2022 at "Marine Drugs"
DOI: 10.3390/md20030179
Abstract: Several natural products recovered from a marine-derived Aspergillus niger were tested for their inhibitory activity against SARS CoV-2 in vitro. Aurasperone A (3) was found to inhibit SARS CoV-2 efficiently (IC50 = 12.25 µM) with… read more here.
Keywords: aurasperone; sars cov; vitro integrated; cov vitro ... See more keywords
Prominent Efficacy of Amantadine against Human Borna Disease Virus Infection In Vitro and In Vivo. Comment on Fink et al. Amantadine Inhibits SARS-CoV-2 In Vitro. Viruses 2021, 13, 539
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14030494
Abstract: Amantadine (1-amino-adamantane) is a versatile antiviral compound which has been licensed for decades against influenza viruses. During the Corona pandemic, its effect to inhibit SARS-CoV-2 in vitro has been investigated. However, an in vivo oral… read more here.
Keywords: disease virus; borna disease; sars cov; cov vitro ... See more keywords