Incidence of Guillain-Barré Syndrome After COVID-19 Vaccination in the Vaccine Safety Datalink.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2022.8879
Abstract: Importance Postauthorization monitoring of vaccines in a large population may detect rare adverse events not identified in clinical trials such as Guillain-Barré syndrome (GBS), which has a background rate of 1 to 2 per 100 000… read more here.
Keywords: incidence; vaccination; gbs; rate ... See more keywords
Persistence of Ad26.COV2.S-associated VITT and specific detection of VITT antibodies.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of hematology"
DOI: 10.1002/ajh.26488
Abstract: Rare cases of COVID-19 vaccinated individuals develop anti-platelet factor 4 (PF4) antibodies that cause thrombocytopenia and thrombotic complications, a syndrome referred to as vaccine-induced immune thrombotic thrombocytopenia (VITT). Currently, information on the characteristics and persistence… read more here.
Keywords: cov2; cov2 associated; associated vitt; ad26 cov2 ... See more keywords
Cutaneous small vessel vasculitis following single-dose Janssen Ad26.COV2.S vaccination
Sign Up to like & getrecommendations! Published in 2021 at "JAAD Case Reports"
DOI: 10.1016/j.jdcr.2021.07.002
Abstract: CSVV: cutaneous small vessel vasculitis INTRODUCTION Two single-dose COVID-19 vaccines utilizing the adenoviral vector platform, ChAdOx1 nCoV-19 (AstraZeneca) and Ad26.COV2.S (Janssen), have recently been associated with rare immune-mediated thrombotic events and thrombocytopenia. In response to… read more here.
Keywords: ad26 cov2; vessel vasculitis; small vessel; cov2 ... See more keywords
A homologous or variant booster vaccine after Ad26.COV2.S immunization enhances SARS-CoV-2–specific immune responses in rhesus macaques
Sign Up to like & getrecommendations! Published in 2022 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abm4996
Abstract: Ad26.COV2.S has demonstrated durability and clinical efficacy against symptomatic COVID-19 in humans. In this study, we report the correlates of durability of humoral and cellular immune responses in 20 rhesus macaques immunized with single-shot Ad26.COV2.S… read more here.
Keywords: cov2; immunization; immune responses; ad26 cov2 ... See more keywords
Comparative Effectiveness of mRNA-Based BNT162b2 Vaccine versus Adenovirus Vector-Based Ad26.COV2.S Vaccine for Prevention of COVID-19 among Dialysis Patients.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2021101395
Abstract: Background Studies have demonstrated that mRNA-based SARS-CoV-2 vaccines are highly effective among dialysis patients. Because individual vaccines may be differentially available or acceptable to patients, it is important to understand comparative effectiveness relative to other… read more here.
Keywords: dialysis patients; effectiveness; ad26 cov2; cov2 ... See more keywords
Monocytic-Myeloid Derived Suppressor Cells Suppress T-Cell Responses in Recovered SARS CoV2-Infected Individuals
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.894543
Abstract: Coronavirus disease 2019 (COVID-19) caused by SARS Coronavirus 2 (CoV2) is associated with massive immune activation and hyperinflammatory response. Acute and severe CoV2 infection is characterized by the expansion of myeloid derived suppressor cells (MDSC)… read more here.
Keywords: cov2; cell responses; mdsc; cov2 individuals ... See more keywords
Technical Data of Heterologous Expression and Purification of SARS-CoV-2 Proteases Using Escherichia coli System
Sign Up to like & getrecommendations! Published in 2021 at "Data"
DOI: 10.3390/data6090099
Abstract: The SARS-CoV-2 coronavirus expresses two essential proteases: firstly, the 3Chymotrypsin-like protease (3CLpro) or main protease (Mpro), and secondly, the papain-like protease (PLpro), both of which are considered as viable drug targets for the inhibition of… read more here.
Keywords: coli; cov2; cov proteases; bl21 ... See more keywords