Lysine Covalent Antagonists of Melanoma Inhibitors of Apoptosis Protein.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c01459
Abstract: We have recently reported on Lys-covalent agents that, based on aryl-sulfonyl fluorides, were designed to target binding site Lys 311 in the X-linked inhibitor of apoptosis protein (XIAP). Similar to XIAP, melanoma-IAP (ML-IAP), a less… read more here.
Keywords: iap; covalent; covalent antagonists; antagonists melanoma ... See more keywords