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Published in 2019 at "Immunobiology"
DOI: 10.1016/j.imbio.2019.08.003
Abstract: Alex Law and Paul Levine recall their work to establish the covalent bond between C3 and target surfaces. It started with a naive experiment by analyzing the membrane polypeptides of sheep erythrocytes bound with 125I-labelled…
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Keywords:
covalent binding;
proteins 1972;
1972 1981;
binding story ... See more keywords
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Published in 2019 at "Journal of Luminescence"
DOI: 10.1016/j.jlumin.2018.11.013
Abstract: Abstract The effect of electrostatic interaction and covalent binding on the energy transfer from negatively charged CdSe/CdS/ZnS-COО− and positively charged CdSe/CdS/ZnS-N H 3 + quantum dots to reaction centers of Rb. sphaeroides bacteria (RC) in…
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Keywords:
negatively charged;
covalent binding;
energy transfer;
energy ... See more keywords
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2
Published in 2020 at "Xenobiotica"
DOI: 10.1080/00498254.2020.1817626
Abstract: Abstract The formation of reactive metabolites (RMs) is a problem in drug development that sometimes results in severe hepatotoxicity. As detecting RMs themselves is difficult, a covalent binding assay using expensive radiolabelled tracers is usually…
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Keywords:
covalent binding;
risk assessment;
risk;
binding flutamide ... See more keywords
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Published in 2020 at "Methods and Applications in Fluorescence"
DOI: 10.1088/2050-6120/abc13c
Abstract: The work is aimed at the search of selective fluorescent sensors without using specific artificial receptors, antibodies, enzymes etc. With this end in view, methods based on non-covalent binding of target analytes are sought. We…
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Keywords:
covalent binding;
cetyltrimethylammonium bromide;
selective fluorescent;
carbocyanine dye ... See more keywords
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1
Published in 2018 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.117.078782
Abstract: N-{4-Chloro-2-[(1-oxidopyridin-4-yl)carbonyl]phenyl}-4-(propan-2-yloxy)benzenesulfonamide (MLN3126) is an orally available chemokine C-C motif receptor 9 selective antagonist. In nonclinical pharmacokinetic studies of MLN3126, nonextractable radioactivity was observed in plasma after oral administration of 14C-labeled MLN3126 ([14C]MLN3126) to Sprague-Dawley (SD)…
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Keywords:
chemokine motif;
covalent binding;
mln3126;
covalent ... See more keywords
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2
Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137347
Abstract: Understanding the photophysical properties and stability of near-infrared fluorescent proteins (NIR FPs) based on bacterial phytochromes is of great importance for the design of efficient fluorescent probes for use in cells and in vivo. Previously,…
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Keywords:
double covalent;
impact double;
covalent binding;
binding nir ... See more keywords