The covalent binding story of the complement proteins C3 and C4 (I) 1972-1981.
Sign Up to like & getrecommendations! Published in 2019 at "Immunobiology"
DOI: 10.1016/j.imbio.2019.08.003
Abstract: Alex Law and Paul Levine recall their work to establish the covalent bond between C3 and target surfaces. It started with a naive experiment by analyzing the membrane polypeptides of sheep erythrocytes bound with 125I-labelled… read more here.
Keywords: covalent binding; proteins 1972; 1972 1981; binding story ... See more keywords
Electrostatic interactions and covalent binding effects on the energy transfer between quantum dots and reaction centers of purple bacteria
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Luminescence"
DOI: 10.1016/j.jlumin.2018.11.013
Abstract: Abstract The effect of electrostatic interaction and covalent binding on the energy transfer from negatively charged CdSe/CdS/ZnS-COО− and positively charged CdSe/CdS/ZnS-N H 3 + quantum dots to reaction centers of Rb. sphaeroides bacteria (RC) in… read more here.
Keywords: negatively charged; covalent binding; energy transfer; energy ... See more keywords
Evaluation of covalent binding of flutamide and its risk assessment using 19F-NMR
Sign Up to like & getrecommendations! Published in 2020 at "Xenobiotica"
DOI: 10.1080/00498254.2020.1817626
Abstract: Abstract The formation of reactive metabolites (RMs) is a problem in drug development that sometimes results in severe hepatotoxicity. As detecting RMs themselves is difficult, a covalent binding assay using expensive radiolabelled tracers is usually… read more here.
Keywords: covalent binding; risk assessment; risk; binding flutamide ... See more keywords
Non-covalent binding and selective fluorescent sensing of dipyrone with a carbocyanine dye and cetyltrimethylammonium bromide
Sign Up to like & getrecommendations! Published in 2020 at "Methods and Applications in Fluorescence"
DOI: 10.1088/2050-6120/abc13c
Abstract: The work is aimed at the search of selective fluorescent sensors without using specific artificial receptors, antibodies, enzymes etc. With this end in view, methods based on non-covalent binding of target analytes are sought. We… read more here.
Keywords: covalent binding; cetyltrimethylammonium bromide; selective fluorescent; carbocyanine dye ... See more keywords
Mechanism for Covalent Binding of MLN3126, an Oral Chemokine C-C Motif Receptor 9 Antagonist, to Serum Albumins
Sign Up to like & getrecommendations! Published in 2018 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.117.078782
Abstract: N-{4-Chloro-2-[(1-oxidopyridin-4-yl)carbonyl]phenyl}-4-(propan-2-yloxy)benzenesulfonamide (MLN3126) is an orally available chemokine C-C motif receptor 9 selective antagonist. In nonclinical pharmacokinetic studies of MLN3126, nonextractable radioactivity was observed in plasma after oral administration of 14C-labeled MLN3126 ([14C]MLN3126) to Sprague-Dawley (SD)… read more here.
Keywords: chemokine motif; covalent binding; mln3126; covalent ... See more keywords
Impact of Double Covalent Binding of BV in NIR FPs on Their Spectral and Physicochemical Properties
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137347
Abstract: Understanding the photophysical properties and stability of near-infrared fluorescent proteins (NIR FPs) based on bacterial phytochromes is of great importance for the design of efficient fluorescent probes for use in cells and in vivo. Previously,… read more here.
Keywords: double covalent; impact double; covalent binding; binding nir ... See more keywords