Reactive chemistry for covalent probe and therapeutic development.
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DOI: 10.1016/j.tips.2021.12.002
Abstract: Bioactive small molecules that form covalent bonds with a target protein are important tools for basic research and can be highly effective drugs. This review highlights reactive groups found in a collection of thiophilic and… read more here.
Keywords: chemistry; covalent probe; covalent; probe therapeutic ... See more keywords