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Published in 2024 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.4c00277
Abstract: Several novel and effective cysteine targeting (Cys) covalent drugs are in clinical use. However, the target area containing a druggable Cys residue is limited. Therefore, methods for creating covalent drugs that target different residues are…
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Keywords:
covalent stapled;
covalent;
alpha helical;
histidine covalent ... See more keywords