Articles with "covalent stapled" as a keyword



Histidine-Covalent Stapled Alpha-Helical Peptides Targeting hMcl-1

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Published in 2024 at "Journal of Medicinal Chemistry"

DOI: 10.1021/acs.jmedchem.4c00277

Abstract: Several novel and effective cysteine targeting (Cys) covalent drugs are in clinical use. However, the target area containing a druggable Cys residue is limited. Therefore, methods for creating covalent drugs that target different residues are… read more here.

Keywords: covalent stapled; covalent; alpha helical; histidine covalent ... See more keywords