Tuning Enzyme Thermostability via Computationally Guided Covalent Stapling and Structural Basis of Enhanced Stabilization
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DOI: 10.1021/acs.biochem.2c00033
Abstract: Enhancing the thermostability of enzymes without impacting their catalytic function represents an important yet challenging goal in protein engineering and biocatalysis. We recently introduced a novel method for enzyme thermostabilization that relies on the computationally… read more here.
Keywords: stabilization; covalent stapling; structural basis; thermostability ... See more keywords