Thirteen dubious ways to detect conserved structural RNAs
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DOI: 10.1002/iub.2694
Abstract: Covariation induced by compensatory base substitutions in RNA alignments is a great way to deduce conserved RNA structure, in principle. In practice, success depends on many factors, importantly the quality and depth of the alignment… read more here.
Keywords: rna structure; covariation; conserved rna; thirteen dubious ... See more keywords
Covariation between spontaneous neural activity in the insula and affective temperaments is related to sleep disturbance in individuals with major depressive disorder
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DOI: 10.1017/s0033291719003647
Abstract: Abstract Background Affective temperaments have been considered antecedents of major depressive disorder (MDD). However, little is known about how the covariation between alterations in brain activity and distinct affective temperaments work collaboratively to contribute to… read more here.
Keywords: insula; major depressive; depressive disorder; activity ... See more keywords
Grey matter covariation and the role of emotion reappraisal in mental wellbeing and resilience after early life stress exposure
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DOI: 10.1038/s41398-022-01849-6
Abstract: Resilience is a process of adaptive recovery crucial in maintaining mental wellbeing after stress exposure. A psychological factor known to buffer stress and promote positive wellbeing outcomes is the ability to regulate emotions. However, the… read more here.
Keywords: mental wellbeing; stress; exposure; covariation ... See more keywords
In silico analysis of local RNA secondary structure in influenza virus A, B and C finds evidence of widespread ordered stability but little evidence of significant covariation
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DOI: 10.1038/s41598-021-03767-x
Abstract: Influenza virus is a persistent threat to human health; indeed, the deadliest modern pandemic was in 1918 when an H1N1 virus killed an estimated 50 million people globally. The intent of this work is to… read more here.
Keywords: influenza virus; covariation; evidence; influenza ... See more keywords
Functional topography of the neocortex predicts covariation in complex cognitive and basic motor abilities.
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DOI: 10.1093/cercor/bhad109
Abstract: Although higher-order cognitive and lower-order sensorimotor abilities are generally regarded as distinct and studied separately, there is evidence that they not only covary but also that this covariation increases across the lifespan. This pattern has… read more here.
Keywords: covariation; topography; functional topography; basic motor ... See more keywords
Temporal covariation of epibacterial community and surface metabolome in the Mediterranean seaweed holobiont Taonia atomaria.
Sign Up to like & getrecommendations! Published in 2019 at "Environmental microbiology"
DOI: 10.1111/1462-2920.14617
Abstract: An integrative multi-omics approach allowed monthly variations for a year of the surface metabolome and the epibacterial community of the Mediterranean Phaeophyceae Taonia atomaria to be investigated. The LC-MS-based metabolomics and 16S rDNA metabarcoding data… read more here.
Keywords: community; covariation; taonia atomaria; epibacterial community ... See more keywords
COCOA: coordinate covariation analysis of epigenetic heterogeneity
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DOI: 10.1186/s13059-020-02139-4
Abstract: A key challenge in epigenetics is to determine the biological significance of epigenetic variation among individuals. We present Coordinate Covariation Analysis (COCOA), a computational framework that uses covariation of epigenetic signals across individuals and a… read more here.
Keywords: covariation analysis; covariation; coordinate covariation; epigenetic heterogeneity ... See more keywords
RNA structure prediction using positive and negative evolutionary information
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DOI: 10.1371/journal.pcbi.1008387
Abstract: Knowing the structure of conserved structural RNAs is important to elucidate their function and mechanism of action. However, predicting a conserved RNA structure remains unreliable, even when using a combination of thermodynamic stability and evolutionary… read more here.
Keywords: negative evolutionary; covariation; evolutionary information; structure ... See more keywords
Covariation of the endocranium and splanchnocranium during great ape ontogeny
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DOI: 10.1371/journal.pone.0208999
Abstract: That great ape endocranial shape development persists into adolescence indicates that the splanchnocranium succeeds brain growth in driving endocranial development. However, the extent of this splanchnocranial influence is unknown. We applied two-block partial least squares… read more here.
Keywords: splanchnocranium; covariation endocranium; shape; covariation ... See more keywords
Comparing covariation among vaccine hesitancy and broader beliefs within Twitter and survey data
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DOI: 10.1371/journal.pone.0239826
Abstract: Over the past decade, the percentage of adults in the United States who use some form of social media has roughly doubled, increasing from 36 percent in early 2009 to 72 percent in 2019. There… read more here.
Keywords: survey data; covariation; vaccine hesitancy; survey ... See more keywords
Evidence of Differences in Covariation Among Root Traits Across Plant Growth Forms, Mycorrhizal Types, and Biomes
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DOI: 10.3389/fpls.2021.785589
Abstract: Fine roots play an important role in plant ecological strategies, adaptation to environmental constraints, and ecosystem functions. Covariation among root traits influence the physiological and ecological processes of plants and ecosystems. Root trait covariation in… read more here.
Keywords: root traits; covariation; plant growth; root ... See more keywords