Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating
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DOI: 10.1016/j.celrep.2018.07.004
Abstract: SUMMARY The proteasome is the central protease for intracellular protein breakdown. Coordinated binding and hydrolysis of ATP by the six proteasomal ATPase subunits induces conformational changes that drive the unfolding and translocation of substrates into… read more here.
Keywords: conformational landscape; coverage 26s; landscape reveals; expanded coverage ... See more keywords