Validating Amino Acid Variants in Proteogenomics Using Sequence Coverage by Multiple Reads.
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DOI: 10.1021/acs.jproteome.2c00033
Abstract: Mass spectrometry-based proteome analysis implies matching the mass spectra of proteolytic peptides to amino acid sequences predicted from genomic sequences. Reliability of peptide variant identification in proteogenomic studies is often lacking. We propose a way… read more here.
Keywords: sequence coverage; coverage multiple; amino acid; multiple reads ... See more keywords