Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-04668-w
Abstract: Lipoprotein(a), Lp(a), is a modified low-density lipoprotein particle that contains apolipoprotein(a), encoded by LPA, and is a highly heritable, causal risk factor for cardiovascular diseases that varies in concentrations across ancestries. Here, we use deep-coverage… read more here.
Keywords: coverage whole; whole genome; deep coverage; individuals european ... See more keywords
Low-coverage whole-genome sequencing of extracellular vesicle-associated DNA in patients with metastatic cancer
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-83436-1
Abstract: Low-coverage whole-genome sequencing (LC-WGS) can provide insight into oncogenic molecular changes. Serum extracellular vesicles (EV) represent a novel liquid biopsy source of tumoral DNA. This study compared copy number alteration (CNA) profiles generated from LC-WGS… read more here.
Keywords: coverage whole; low coverage; whole genome; range ... See more keywords
Testing the systematic status of Homalictus and Rostrohalictus with weakened cross-vein groups within Halictini (Hymenoptera: Halictidae) using low-coverage whole-genome sequencing.
Sign Up to like & getrecommendations! Published in 2022 at "Insect science"
DOI: 10.1111/1744-7917.13034
Abstract: The halictid genus Lasioglossum, as one of the most species-rich bee groups with persistently contentious subgeneric boundaries, is one of the most challenging bee groups from a systematic standpoint. An enduring question is the relationship… read more here.
Keywords: rostrohalictus; lasioglossum; low coverage; status ... See more keywords
Cost-effective low-coverage whole-genome sequencing assay for the risk stratification of gastric cancer
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Gastrointestinal Oncology"
DOI: 10.4251/wjgo.v14.i3.690
Abstract: BACKGROUND Gastric cancer (GC), a multifactorial disease, is caused by pathogens, such as Helicobacter pylori (H. pylori) and Epstein-Barr virus (EBV), and genetic components. AIM To investigate microbiomes and host genome instability by cost-effective, low-coverage… read more here.
Keywords: genome sequencing; coverage; genome; low coverage ... See more keywords