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   Articles with "covid pathogenesis" as a keyword



Partners in crime: Autoantibodies complicit in COVID‐19 pathogenesis

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recommendations! Published in 2022 at "Reviews in Medical Virology"

DOI: 10.1002/rmv.2412

Abstract: Autoantibodies (AABs) play a critical role in the pathogenesis of autoimmune diseases (AIDs) and serve as a diagnostic and prognostic tool in assessing these complex disorders. Viral infections have long been recognized as a principal… read more here.

Keywords: complicit covid; crime autoantibodies; partners crime; covid pathogenesis ... See more keywords

Virus‐Induced Host Chemokine CCL2 in COVID‐19 Pathogenesis: Potential Prognostic Marker and Target of Anti‐Inflammatory Strategy

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recommendations! Published in 2024 at "Reviews in Medical Virology"

DOI: 10.1002/rmv.2578

Abstract: A wide variety of inflammatory mediators, mainly cytokines and chemokines, are induced during SARS CoV‐2 infection. Among these proinflammatory mediators, chemokines tend to play a pivotal role in virus‐mediated immunopathology. The C‐C chemokine ligand 2… read more here.

Keywords: ccl2; virus; chemokine; covid pathogenesis ... See more keywords
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Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment

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recommendations! Published in 2020 at "Cell"

DOI: 10.1016/j.cell.2020.06.010

Abstract: Summary COVID-19, caused by SARS-CoV-2, is a virulent pneumonia, with >4,000,000 confirmed cases worldwide and >290,000 deaths as of May 15, 2020. It is critical that vaccines and therapeutics be developed very rapidly. Mice, the… read more here.

Keywords: covid pathogenesis; generation broadly; covid; model ... See more keywords

COVID-19: Pathogenesis and Clinical Manifestations

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recommendations! Published in 2022 at "Infectious Disease Clinics of North America"

DOI: 10.1016/j.idc.2022.01.003

Abstract: Synopsis: In this review, we summarize the current knowledge about the virology, the host-pathogen interactions and mechanisms of disease of coronavirus disease 2019 (COVID-19) in humans. We also describe the various clinical presentations of the… read more here.

Keywords: covid pathogenesis; clinical manifestations; disease; pathogenesis clinical ... See more keywords

Poly(A) tail dynamics, non-adenine incorporation and alternative polyadenylation shape the host transcriptome in COVID-19 pathogenesis

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-21969-5

Abstract: The COVID-19 pandemic has had a profound global impact since its emergence in late 2019. Characterized by a wide spectrum of clinical manifestations, COVID-19 has necessitated extensive research into the host-pathogen interactions that drive disease… read more here.

Keywords: non adenine; poly tail; covid pathogenesis; host ... See more keywords

Detection of the Serum Cytokines Predicts COVID-19 Pathogenesis in Egyptian Patients.

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recommendations! Published in 2022 at "Viral immunology"

DOI: 10.1089/vim.2021.0170

Abstract: Cytokine storms can be triggered by various infectious or noninfectious diseases and cause severe damages to multiple organs. Cytokine storm plays an important role in the pathogenesis of severe cases of coronavirus disease 2019 (COVID-19).… read more here.

Keywords: critically ill; serum; serum cytokines; covid pathogenesis ... See more keywords
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Critical Determinants of Cytokine Storm and Type I Interferon Response in COVID-19 Pathogenesis

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recommendations! Published in 2021 at "Clinical Microbiology Reviews"

DOI: 10.1128/cmr.00299-20

Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), a rapidly evolving pandemic worldwide with at least 68 million COVID-19-positive cases and a mortality rate of about 2.2%, as of 10 December… read more here.

Keywords: cytokine storm; type; sars cov; syndrome ... See more keywords

Mechanisms of COVID-19 pathogenesis in diabetes

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recommendations! Published in 2022 at "American Journal of Physiology - Heart and Circulatory Physiology"

DOI: 10.1152/ajpheart.00204.2022

Abstract: Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) virus, is a global pandemic impacting 254 million people in 190 countries. Comorbidities, particularly cardiovascular disease, diabetes, and hypertension, in-crease the… read more here.

Keywords: mechanisms covid; disease; physiology; covid pathogenesis ... See more keywords

Role of Monocytes/Macrophages in Covid-19 Pathogenesis: Implications for Therapy

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recommendations! Published in 2020 at "Infection and Drug Resistance"

DOI: 10.2147/idr.s258639

Abstract: cov-Abstract Emerging studies from SARS-CoV-2-infected patients indicate a preponderant role of monocytes/macrophages in the pathogenesis of this viral infection, in a similar way to that previously observed in other coronavirus outbreaks (SARS and MERS). The… read more here.

Keywords: role; role monocytes; coronavirus outbreaks; monocytes macrophages ... See more keywords

New evidence for T-cadherin in COVID-19 pathogenesis, endothelial dysfunction, and lung fibrosis

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recommendations! Published in 2025 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2025.1476329

Abstract: The COVID-19 pandemic had an unprecedented impact on all aspects of human activity worldwide, frequently resulting in post-acute sequelae and affecting multiple organ systems. The underlying mechanisms driving both acute and post-acute manifestations of COVID-19… read more here.

Keywords: cadherin covid; endothelial dysfunction; expression; cadherin ... See more keywords

Hallmarks of Severe COVID-19 Pathogenesis: A Pas de Deux Between Viral and Host Factors

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recommendations! Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.912336

Abstract: Two years into Coronavirus Disease 2019 (COVID-19) pandemic, a comprehensive characterization of the pathogenesis of severe and critical forms of COVID-19 is still missing. While a deep dysregulation of both the magnitude and functionality of… read more here.

Keywords: severe covid; host factors; viral host; covid ... See more keywords