Partners in crime: Autoantibodies complicit in COVID‐19 pathogenesis
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DOI: 10.1002/rmv.2412
Abstract: Autoantibodies (AABs) play a critical role in the pathogenesis of autoimmune diseases (AIDs) and serve as a diagnostic and prognostic tool in assessing these complex disorders. Viral infections have long been recognized as a principal… read more here.
Keywords: complicit covid; crime autoantibodies; partners crime; covid pathogenesis ... See more keywords
Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment
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DOI: 10.1016/j.cell.2020.06.010
Abstract: Summary COVID-19, caused by SARS-CoV-2, is a virulent pneumonia, with >4,000,000 confirmed cases worldwide and >290,000 deaths as of May 15, 2020. It is critical that vaccines and therapeutics be developed very rapidly. Mice, the… read more here.
Keywords: covid pathogenesis; generation broadly; covid; model ... See more keywords
COVID-19: Pathogenesis and Clinical Manifestations
Sign Up to like & getrecommendations! Published in 2022 at "Infectious Disease Clinics of North America"
DOI: 10.1016/j.idc.2022.01.003
Abstract: Synopsis: In this review, we summarize the current knowledge about the virology, the host-pathogen interactions and mechanisms of disease of coronavirus disease 2019 (COVID-19) in humans. We also describe the various clinical presentations of the… read more here.
Keywords: covid pathogenesis; clinical manifestations; disease; pathogenesis clinical ... See more keywords
Detection of the Serum Cytokines Predicts COVID-19 Pathogenesis in Egyptian Patients.
Sign Up to like & getrecommendations! Published in 2022 at "Viral immunology"
DOI: 10.1089/vim.2021.0170
Abstract: Cytokine storms can be triggered by various infectious or noninfectious diseases and cause severe damages to multiple organs. Cytokine storm plays an important role in the pathogenesis of severe cases of coronavirus disease 2019 (COVID-19).… read more here.
Keywords: critically ill; serum; serum cytokines; covid pathogenesis ... See more keywords
Critical Determinants of Cytokine Storm and Type I Interferon Response in COVID-19 Pathogenesis
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DOI: 10.1128/cmr.00299-20
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), a rapidly evolving pandemic worldwide with at least 68 million COVID-19-positive cases and a mortality rate of about 2.2%, as of 10 December… read more here.
Keywords: cytokine storm; type; sars cov; syndrome ... See more keywords
Mechanisms of COVID-19 pathogenesis in diabetes
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Physiology - Heart and Circulatory Physiology"
DOI: 10.1152/ajpheart.00204.2022
Abstract: Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) virus, is a global pandemic impacting 254 million people in 190 countries. Comorbidities, particularly cardiovascular disease, diabetes, and hypertension, in-crease the… read more here.
Keywords: mechanisms covid; disease; physiology; covid pathogenesis ... See more keywords
Role of Monocytes/Macrophages in Covid-19 Pathogenesis: Implications for Therapy
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DOI: 10.2147/idr.s258639
Abstract: cov-Abstract Emerging studies from SARS-CoV-2-infected patients indicate a preponderant role of monocytes/macrophages in the pathogenesis of this viral infection, in a similar way to that previously observed in other coronavirus outbreaks (SARS and MERS). The… read more here.
Keywords: role; role monocytes; coronavirus outbreaks; monocytes macrophages ... See more keywords
Hallmarks of Severe COVID-19 Pathogenesis: A Pas de Deux Between Viral and Host Factors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.912336
Abstract: Two years into Coronavirus Disease 2019 (COVID-19) pandemic, a comprehensive characterization of the pathogenesis of severe and critical forms of COVID-19 is still missing. While a deep dysregulation of both the magnitude and functionality of… read more here.
Keywords: severe covid; host factors; viral host; covid ... See more keywords
Circular RNAs as emerging regulators in COVID-19 pathogenesis and progression
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.980231
Abstract: Coronavirus disease 2019 (COVID-19), an infectious acute respiratory disease caused by a newly emerging RNA virus, is a still-growing pandemic that has caused more than 6 million deaths globally and has seriously threatened the lives… read more here.
Keywords: emerging regulators; rnas emerging; pathogenesis progression; circular rnas ... See more keywords