LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "covr" as a keyword



The virulence regulator CovR boosts CRISPR-Cas9 immunity in Group B Streptococcus

Sign Up to like & get
recommendations! Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-60871-6

Abstract: CRISPR-Cas9 immune systems protect bacteria from foreign DNA. However, immune efficiency is constrained by Cas9 off-target cleavages and toxicity. How bacteria regulate Cas9 to maximize protection while preventing autoimmunity is not understood. Here, we show… read more here.

Keywords: covr; immunity; virulence; regulator ... See more keywords

VicRK and CovR polymorphisms in Streptococcus mutans strains associated with cardiovascular infections.

Sign Up to like & get
recommendations! Published in 2021 at "Journal of medical microbiology"

DOI: 10.1099/jmm.0.001457

Abstract: Introduction. Streptococcus mutans, a common species of the oral microbiome, expresses virulence genes promoting cariogenic dental biofilms, persistence in the bloodstream and cardiovascular infections.Gap statement. Virulence gene expression is variable among S. mutans strains and… read more here.

Keywords: mutans strains; streptococcus mutans; covr; blood ... See more keywords

Role of CovR phosphorylation in gene transcription in Streptococcus mutans.

Sign Up to like & get
recommendations! Published in 2018 at "Microbiology"

DOI: 10.1099/mic.0.000641

Abstract: Streptococcus mutans, the primary aetiological agent of dental caries, is one of the major bacteria of the human oral cavity. The pathogenicity of this bacterium is attributed not only to the expression of virulence factors,… read more here.

Keywords: covr phosphorylation; covr; role covr; phosphorylation ... See more keywords

Streptolysin O Deficiency in Streptococcus pyogenes M1T1 covR/S Mutant Strain Attenuates Virulence in In Vitro and In Vivo Infection Models

Sign Up to like & get
recommendations! Published in 2023 at "mBio"

DOI: 10.1128/mbio.03488-22

Abstract: Streptococcus pyogenes is responsible for significant numbers of invasive and noninvasive infections which cause significant morbidity and mortality globally. Strep A isolates with mutations in the covR/S system display greater propensity to cause severe invasive… read more here.

Keywords: covr; virulence; streptococcus pyogenes; slo ... See more keywords

Reduced interleukin-18 secretion by human monocytic cells in response to infections with hyper-virulent Streptococcus pyogenes

Sign Up to like & get
recommendations! Published in 2024 at "Journal of Biomedical Science"

DOI: 10.1186/s12929-024-01014-9

Abstract: Streptococcus pyogenes (group A streptococcus, GAS) causes a variety of diseases ranging from mild superficial infections of the throat and skin to severe invasive infections, such as necrotizing soft tissue infections (NSTIs). Tissue passage of… read more here.

Keywords: covr; streptococcus; response; gas ... See more keywords