VicRK and CovR polymorphisms in Streptococcus mutans strains associated with cardiovascular infections.
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DOI: 10.1099/jmm.0.001457
Abstract: Introduction. Streptococcus mutans, a common species of the oral microbiome, expresses virulence genes promoting cariogenic dental biofilms, persistence in the bloodstream and cardiovascular infections.Gap statement. Virulence gene expression is variable among S. mutans strains and… read more here.
Keywords: mutans strains; streptococcus mutans; covr; blood ... See more keywords
Role of CovR phosphorylation in gene transcription in Streptococcus mutans.
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DOI: 10.1099/mic.0.000641
Abstract: Streptococcus mutans, the primary aetiological agent of dental caries, is one of the major bacteria of the human oral cavity. The pathogenicity of this bacterium is attributed not only to the expression of virulence factors,… read more here.
Keywords: covr phosphorylation; covr; role covr; phosphorylation ... See more keywords
Streptolysin O Deficiency in Streptococcus pyogenes M1T1 covR/S Mutant Strain Attenuates Virulence in In Vitro and In Vivo Infection Models
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DOI: 10.1128/mbio.03488-22
Abstract: Streptococcus pyogenes is responsible for significant numbers of invasive and noninvasive infections which cause significant morbidity and mortality globally. Strep A isolates with mutations in the covR/S system display greater propensity to cause severe invasive… read more here.
Keywords: covr; virulence; streptococcus pyogenes; slo ... See more keywords