Effect of antibiotics and NSAIDs on cyclooxygenase-2 in the enamel mineralization
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-22607-z
Abstract: The objective of this study was to determine whether the use of the most commonly prescribed antibiotics and non-steroidal anti-inflammatory drugs in childhood could disturb enamel mineralization. Forty-two Swiss mice were divided into seven groups:… read more here.
Keywords: antibiotics nsaids; nsaids cyclooxygenase; effect antibiotics; cox2 ... See more keywords
Graphene oxide regulates cox2 in human embryonic kidney 293T cells via epigenetic mechanisms: dynamic chromosomal interactions
Sign Up to like & getrecommendations! Published in 2018 at "Nanotoxicology"
DOI: 10.1080/17435390.2018.1425498
Abstract: Abstract To extend the applications of engineered nanomaterials, such as graphene oxide (GO), it is necessary to minimize cytotoxicity. However, the mechanisms underlying this cytotoxicity are unclear. Dynamic chromosomal interactions have been used to illustrate… read more here.
Keywords: graphene oxide; chromosomal interactions; embryonic kidney; dynamic chromosomal ... See more keywords
Role of circRNA circ_0000080 in myocardial hypoxia injury
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2066752
Abstract: ABSTRACT This study aimed to investigate the potential role of circRNA circ_0000080 in myocardial hypoxia injury and the underlying mechanisms. Patients with myocardial hypoxia injury who were admitted to Xi’an No. 1 Hospital, China, were… read more here.
Keywords: circ 0000080; cox2; myocardial hypoxia; hypoxia injury ... See more keywords
739. SIGNIFICANCE OF COX2 INHIBITOR FOR ESOPHAGEAL CANCER FROM THE CLINICAL AND EXPERIMENTAL ESTIMATE
Sign Up to like & getrecommendations! Published in 2024 at "Diseases of the Esophagus"
DOI: 10.1093/dote/doae057.352
Abstract: (Aims) We report experimental and clinical evidence that COX2 represent a potential molecular target for the treatment and prevention of esophageal cancer. (Methods) (A)Experiment: Thirty 8-week male wistar rats were exposed to duodenal content esophageal… read more here.
Keywords: esophageal; esophageal cancer; expression cox2; cox2 ... See more keywords
First report of white blister rust disease caused by Albugo occidentalis on Spinach in Turkey
Sign Up to like & getrecommendations! Published in 2017 at "Plant Disease"
DOI: 10.1094/pdis-10-17-1561-pdn
Abstract: Spinach (Spinacia oleracea L.) is an increasingly important vegetable crop in Turkey as is the case for many parts of the world. In March 2017, detailed field surveys were conducted to investigate the occurrence of… read more here.
Keywords: spinach; turkey; blister rust; disease ... See more keywords
The COX2 Effector Microsomal PGE2 Synthase 1 is a Regulator of Immunosuppression in Cutaneous Melanoma
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-18-1163
Abstract: Purpose: Microsomal prostaglandin E2 synthase 1 (mPGES1) was evaluated as an important downstream effector of the COX2 pathway responsible for tumor-mediated immunosuppression in melanoma. Experimental Design: The analysis of a stage III melanoma tissue microarray… read more here.
Keywords: melanoma; synthase; cox2; immunosuppression ... See more keywords
Abstract LB-399: Aspirin reduces doxorubicin-induced senescence and early-aging in mice
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-lb-399
Abstract: Survivors of childhood cancers are often associated with the adverse late effects of earlier cancer treatments, including hearing loss, early menopause, osteoporosis, hypoplasia, fatigue, and infertility. While an accumulating body of evidence supports the hypothesis… read more here.
Keywords: senescence early; senescence; early aging; mice ... See more keywords
Spatiotemporally distinct roles of cyclooxygenase-1 and cyclooxygenase-2 at fetomaternal interface in mice
Sign Up to like & getrecommendations! Published in 2024 at "JCI Insight"
DOI: 10.1172/jci.insight.181865
Abstract: Embryo implantation is crucial for ensuring a successful pregnancy outcome and subsequent child health. The intrauterine environment during the peri-implantation period shows drastic changes in gene expression and cellular metabolism in response to hormonal stimuli… read more here.
Keywords: mice; distinct roles; cox2; implantation ... See more keywords
Mutant KRAS Enhances Stress Granules and Resistance to Proteasome Inhibition Via 15-d-PGJ2 in Multiple Myeloma
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-130493
Abstract: Introduction: Mutant KRAS leads to activation of the MEK/ERK pathway in approximately 20% of multiple myeloma (MM) patients. Stress granules (SGs) are cytosolic non-membranous structures composed of translational mRNAs, ribosomal proteins, and RNA-binding proteins, which… read more here.
Keywords: mutant kras; krasm; formation; stress ... See more keywords
Aspirin mediates protection from diabetic kidney disease by inducing ferroptosis inhibition
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0279010
Abstract: Diabetic kidney disease (DKD) progression can be predicted by abnormalities in the tubulointerstitial lining, and their treatment may be useful for preventing the disease. DKD is a progressive disease that contributes to renal tubular cell… read more here.
Keywords: dkd; cox2; disease; diabetic kidney ... See more keywords
Inhibition of lincRNA-Cox2 alleviates apoptosis and inflammatory injury of lipopolysaccharide-stimulated human bronchial epithelial cells via the Nrf2/HO-1 axis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Biochemistry and Nutrition"
DOI: 10.3164/jcbn.22-102
Abstract: This study mainly explored the role and mechanism of lincRNA-Cox2 in inflammatory injury of human bronchial epithelial cells. BEAS-2B cells were stimulated with lipopolysaccharide to establish an in vitro inflammatory injury model. Real-time polymerase chain… read more here.
Keywords: inflammatory injury; lincrna cox2; human bronchial; cox2 ... See more keywords