Effect of antibiotics and NSAIDs on cyclooxygenase-2 in the enamel mineralization
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-22607-z
Abstract: The objective of this study was to determine whether the use of the most commonly prescribed antibiotics and non-steroidal anti-inflammatory drugs in childhood could disturb enamel mineralization. Forty-two Swiss mice were divided into seven groups:… read more here.
Keywords: antibiotics nsaids; nsaids cyclooxygenase; effect antibiotics; cox2 ... See more keywords
Graphene oxide regulates cox2 in human embryonic kidney 293T cells via epigenetic mechanisms: dynamic chromosomal interactions
Sign Up to like & getrecommendations! Published in 2018 at "Nanotoxicology"
DOI: 10.1080/17435390.2018.1425498
Abstract: Abstract To extend the applications of engineered nanomaterials, such as graphene oxide (GO), it is necessary to minimize cytotoxicity. However, the mechanisms underlying this cytotoxicity are unclear. Dynamic chromosomal interactions have been used to illustrate… read more here.
Keywords: graphene oxide; chromosomal interactions; embryonic kidney; dynamic chromosomal ... See more keywords
Role of circRNA circ_0000080 in myocardial hypoxia injury
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2066752
Abstract: ABSTRACT This study aimed to investigate the potential role of circRNA circ_0000080 in myocardial hypoxia injury and the underlying mechanisms. Patients with myocardial hypoxia injury who were admitted to Xi’an No. 1 Hospital, China, were… read more here.
Keywords: circ 0000080; cox2; myocardial hypoxia; hypoxia injury ... See more keywords
First report of white blister rust disease caused by Albugo occidentalis on Spinach in Turkey
Sign Up to like & getrecommendations! Published in 2017 at "Plant Disease"
DOI: 10.1094/pdis-10-17-1561-pdn
Abstract: Spinach (Spinacia oleracea L.) is an increasingly important vegetable crop in Turkey as is the case for many parts of the world. In March 2017, detailed field surveys were conducted to investigate the occurrence of… read more here.
Keywords: spinach; turkey; blister rust; disease ... See more keywords
The COX2 Effector Microsomal PGE2 Synthase 1 is a Regulator of Immunosuppression in Cutaneous Melanoma
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-18-1163
Abstract: Purpose: Microsomal prostaglandin E2 synthase 1 (mPGES1) was evaluated as an important downstream effector of the COX2 pathway responsible for tumor-mediated immunosuppression in melanoma. Experimental Design: The analysis of a stage III melanoma tissue microarray… read more here.
Keywords: melanoma; synthase; cox2; immunosuppression ... See more keywords
Abstract LB-399: Aspirin reduces doxorubicin-induced senescence and early-aging in mice
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-lb-399
Abstract: Survivors of childhood cancers are often associated with the adverse late effects of earlier cancer treatments, including hearing loss, early menopause, osteoporosis, hypoplasia, fatigue, and infertility. While an accumulating body of evidence supports the hypothesis… read more here.
Keywords: senescence early; senescence; early aging; mice ... See more keywords
Mutant KRAS Enhances Stress Granules and Resistance to Proteasome Inhibition Via 15-d-PGJ2 in Multiple Myeloma
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-130493
Abstract: Introduction: Mutant KRAS leads to activation of the MEK/ERK pathway in approximately 20% of multiple myeloma (MM) patients. Stress granules (SGs) are cytosolic non-membranous structures composed of translational mRNAs, ribosomal proteins, and RNA-binding proteins, which… read more here.
Keywords: mutant kras; krasm; formation; stress ... See more keywords
Aspirin mediates protection from diabetic kidney disease by inducing ferroptosis inhibition
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0279010
Abstract: Diabetic kidney disease (DKD) progression can be predicted by abnormalities in the tubulointerstitial lining, and their treatment may be useful for preventing the disease. DKD is a progressive disease that contributes to renal tubular cell… read more here.
Keywords: dkd; cox2; disease; diabetic kidney ... See more keywords
Inhibition of lincRNA-Cox2 alleviates apoptosis and inflammatory injury of lipopolysaccharide-stimulated human bronchial epithelial cells via the Nrf2/HO-1 axis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Biochemistry and Nutrition"
DOI: 10.3164/jcbn.22-102
Abstract: This study mainly explored the role and mechanism of lincRNA-Cox2 in inflammatory injury of human bronchial epithelial cells. BEAS-2B cells were stimulated with lipopolysaccharide to establish an in vitro inflammatory injury model. Real-time polymerase chain… read more here.
Keywords: inflammatory injury; lincrna cox2; human bronchial; cox2 ... See more keywords
Computational Design, Synthesis, and Pharmacological Evaluation of Naproxen-Guaiacol Chimera for Gastro-Sparing Anti-Inflammatory Response by Selective COX2 Inhibition
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27206905
Abstract: The 4-allyl guaiacol is a natural phenolic molecule that has been widely studied for its antioxidant capacity against reactive-oxygen-species-mediated cellular damage. Therefore, we hypothesized that concomitant use of an antioxidant and NSAID may decrease the… read more here.
Keywords: guaiacol; cox2; chimera; anti inflammatory ... See more keywords
Study of the relation between two common cyclooxygenase 2 gene polymorphisms with risk of developing and subtypes of vitiligo in Egyptian patients
Sign Up to like & getrecommendations! Published in 2018 at "Indian Journal of Dermatology, Venereology and Leprology"
DOI: 10.4103/ijdvl.ijdvl_813_16
Abstract: Background/Purpose: Genetic factors play an important role in the pathogenesis of vitiligo. Cyclooxygenase 2 (COX2) gene induced by ultraviolet radiation controls the synthesis of prostaglandins, which are are found to be beneficial in treating vitiligo.… read more here.
Keywords: vitiligo; relation two; two common; cox2 ... See more keywords