Deletion of cox7c Results in Pan-Azole Resistance in Aspergillus fumigatus
Sign Up to like & getrecommendations! Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00151-22
Abstract: In Aspergillus fumigatus, the most prevalent resistance to azoles results from mutational modifications of the azole target protein Cyp51A, but there are non-cyp51A mutants resistant to azoles, and the mechanisms underlying the resistance of these… read more here.
Keywords: deletion; aspergillus fumigatus; resistance; azole resistance ... See more keywords
The nuclear encoded Cox7c mRNA co-transport with mitochondria along axons via coding-region dependent mechanism.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cell science"
DOI: 10.1242/jcs.259436
Abstract: Nuclear encoded mitochondrial protein mRNAs have been found to be localized and locally translated within neuronal processes. However, the transport mechanism of those mRNAs to distal locations is not fully understood. Here, we describe axonal… read more here.
Keywords: coding region; cox7c; transport; cox7c mrna ... See more keywords
Effect of Dl-3-n-butylphthalide on mitochondrial Cox7c in models of cerebral ischemia/reperfusion injury
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1084564
Abstract: Several studies have demonstrated the protective effect of dl-3-n-Butylphthalide (NBP) against cerebral ischemia, which may be related to the attenuation of mitochondrial dysfunction. However, the specific mechanism and targets of NBP in cerebral ischemia/reperfusion remains… read more here.
Keywords: cerebral ischemia; effect butylphthalide; cox7c; ischemia reperfusion ... See more keywords