Biochemical pathway for the biosynthesis of the CuA center in bacterial cytochrome c oxidase
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DOI: 10.1002/1873-3468.13587
Abstract: The di‐copper center CuA is an essential metal cofactor in cytochrome oxidase (Cox) of mitochondria and many prokaryotes, mediating one‐electron transfer from cytochrome c to the site for oxygen reduction. CuA is located in subunit… read more here.
Keywords: cytochrome oxidase; cu2; center; coxb ... See more keywords
Structural basis and mechanism for metallochaperone-assisted assembly of the CuA center in cytochrome oxidase
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aaw8478
Abstract: We demonstrate how two copper atoms are brought together to build a metal center in an essential enzyme for cellular respiration. The mechanisms underlying the biogenesis of the structurally unique, binuclear Cu1.5+•Cu1.5+ redox center (CuA)… read more here.
Keywords: cu2; cu1; cua center; center ... See more keywords