Seroprevalence of coxsackievirus A21 neutralizing antibodies in Yamagata, Japan between 1976 and 2019; coxsackievirus A21 has rarely affected young children.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medical virology"
DOI: 10.1002/jmv.27470
Abstract: Although coxsackievirus A21 (CV-A21) has been associated with acute respiratory infection (ARI) as well as poliomyelitis-like paralysis, reports of CV-A21 detection have been quite limited both globally and in Japan. CV-A21 strains were isolated from… read more here.
Keywords: neutralizing antibodies; young children; coxsackievirus a21; yamagata japan ... See more keywords
A neonatal case of coxsackievirus B3 vertical infection with symptoms of hemophagocytic lymphohistiocytosis
Sign Up to like & getrecommendations! Published in 2020 at "IDCases"
DOI: 10.1016/j.idcr.2020.e00738
Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome of excessive immune activation that most commonly affects infants. We report the case of a term female neonate with HLH associated with coxsackievirus B3 Infection. Her mother was… read more here.
Keywords: life; case; hemophagocytic lymphohistiocytosis; day life ... See more keywords
Bifidobacteria-derived lipoproteins inhibit infection with coxsackievirus B4 in vitro.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2017.03.010
Abstract: The aim of the present study was to investigate the potential of bifidobacteria in protecting cells from coxsackievirus B4 (CV-B4) infection. Bifidobacterial screening identified two of five strains that protected human epithelial type 2 (HEp-2)… read more here.
Keywords: prior inoculation; infection; inhibit infection; bifidobacteria ... See more keywords
Strand-specific affinity of host factor hnRNP C1/C2 guides positive to negative-strand ratio in Coxsackievirus B3 infection
Sign Up to like & getrecommendations! Published in 2019 at "RNA Biology"
DOI: 10.1080/15476286.2019.1629208
Abstract: ABSTRACT Coxsackievirus B3 is an enterovirus, with positive-sense single-stranded RNA genome containing ‘Internal Ribosome Entry Site’ (IRES) in the 5ʹUTR. Once sufficient viral proteins are synthesized in the cell from the input RNA, viral template… read more here.
Keywords: positive negative; hnrnp; strand; negative strand ... See more keywords
Immune mechanisms of group B coxsackievirus induced viral myocarditis
Sign Up to like & getrecommendations! Published in 2023 at "Virulence"
DOI: 10.1080/21505594.2023.2180951
Abstract: ABSTRACT Viral myocarditis is known to be a primary cause of dilated cardiomyopathy (DCM) that can lead to heart failure and sudden cardiac death and is invariably caused by myocardial viral infection following active inflammatory… read more here.
Keywords: myocarditis; mechanisms group; immune mechanisms; coxsackievirus ... See more keywords
Neuropathology in Neonatal Mice After Experimental Coxsackievirus B2 Infection Using a Prototype Strain, Ohio-1.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlz124
Abstract: Coxsackievirus B (CVB) causes severe morbidity and mortality in neonates and is sometimes associated with severe brain damage resulting from acute severe viral encephalomyelitis. However, the neuropathology of CVB infection remains unclear. A prototype strain… read more here.
Keywords: neuropathology; infection; neonatal mice; prototype strain ... See more keywords
Transient atrial inflammation in a murine model of Coxsackievirus B3‐induced myocarditis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Experimental Pathology"
DOI: 10.1111/iep.12438
Abstract: Atrial dysfunction is a relatively common complication of acute myocarditis, although its pathophysiology is unclear. There is limited information on myocarditis‐associated histological changes in the atria and how they develop in time. The aim of… read more here.
Keywords: myocarditis; inflammation; transient atrial; cvb3 ... See more keywords
Immunohistochemical detection of enteroviruses in pancreatic tissues of patients with type 1 diabetes using a polyclonal antibody against 2A protease of Coxsackievirus.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of diabetes investigation"
DOI: 10.1111/jdi.13700
Abstract: INTRODUCTION The need for antiserum for immunohistochemical detection (IHC) of enterovirus (EV) in formaldehyde fixed and paraffin-embedded (FFPE) samples is increasing. The gold standard monoclonal antibody (clone 5D8/1) against EV-envelope protein (VP1) was proven to… read more here.
Keywords: ihc; antibody; immunohistochemical detection; antiserum ... See more keywords
Persistent Coxsackievirus B3 Infection in Pancreatic Ductal Cells In Vitro Downregulates Cellular Polyamine Metabolism
Sign Up to like & getrecommendations! Published in 2023 at "mSphere"
DOI: 10.1128/msphere.00036-23
Abstract: Enteroviruses are significant human pathogens that can cause severe disease, including cardiomyopathies. Viruses like coxsackievirus B3 (CVB3) can cause tissue damage by lytically infecting cells; however, CVB3 can also persistently infect, which has been associated… read more here.
Keywords: infection; infection pancreatic; cvb3; coxsackievirus ... See more keywords
Cleavage of AUF1 by Coxsackievirus B Affects DDX5 Regulatory on Viral Replication through iTRAQ Proteomics Analysis
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/8610467
Abstract: Coxsackievirus B (CVB) 3C protease (3Cpro) plays a specific cleavage role on AU-rich binding factor (AUF1, also called hnRNP D), which consequently disputes the regulation of AUF1 on downstream molecules. In our study, the iTRAQ… read more here.
Keywords: cleavage; replication; auf1 coxsackievirus; cleavage auf1 ... See more keywords
Neutralization of interleukin-38 exacerbates coxsackievirus B3-induced acute myocarditis in mice
Sign Up to like & getrecommendations! Published in 2021 at "Virology Journal"
DOI: 10.1186/s12985-021-01687-w
Abstract: Background Interleukin (IL)-38, a novel member of the IL-1 family, has been reported to be involved in several diseases associated with viral infection. However, the expression and functional role of IL-38 in acute viral myocarditis… read more here.
Keywords: neutralization; expression; myocarditis; mice ... See more keywords