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Building a better particle: Leveraging physicochemical understanding of amorphous solid dispersions and a hierarchical particle approach for improved delivery at high drug loadings

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Published in 2019 at "International Journal of Pharmaceutics"

DOI: 10.1016/j.ijpharm.2019.01.009

Abstract: &NA; Amorphous solid dispersions are a promising option for managing compounds with poor aqueous solubility. However, for compounds with high melting points, thermal stability limitations, or poor solubility in volatile solvents, conventional routes of hot… read more here.

Keywords: solid dispersions; drug; amorphous solid; particle ... See more keywords