Structural similarities in the CPC clip motif explain peptide-binding promiscuity between glycosaminoglycans and lipopolysaccharides
Sign Up to like & getrecommendations! Published in 2017 at "Journal of The Royal Society Interface"
DOI: 10.1098/rsif.2017.0423
Abstract: Lipopolysaccharides (LPSs) and glycosaminoglycans (GAGs) are polymeric structures containing negatively charged disaccharide units that bind to specialized proteins and peptides in the human body and control fundamental processes such as inflammation and coagulation. Surprisingly, some… read more here.
Keywords: clip motif; structural similarities; cpc clip; similarities cpc ... See more keywords
In Silico Analysis of a Drosophila Parasitoid Venom Peptide Reveals Prevalence of the Cation–Polar–Cation Clip Motif in Knottin Proteins
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DOI: 10.3390/pathogens12010143
Abstract: As generalist parasitoid wasps, Leptopilina heterotoma are highly successful on many species of fruit flies of the genus Drosophila. The parasitoids produce specialized multi-strategy extracellular vesicle (EV)-like structures in their venom. Proteomic analysis identified several… read more here.
Keywords: cation; cpc clip; clip motif; knottin ... See more keywords