Articles with "cpeb1" as a keyword



miR-129-3p alleviates chondrocyte apoptosis in knee joint fracture-induced osteoarthritis through CPEB1

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Published in 2020 at "Journal of Orthopaedic Surgery and Research"

DOI: 10.1186/s13018-020-02070-1

Abstract: Background Osteoarthritis (OA), a refractory disease, is one of the leading contributors for disability worldwide. Since chondrocyte is the only resident cell in cartilage, this study aims to explore the roles of miR-129-3p and CPEB1… read more here.

Keywords: chondrocyte apoptosis; cpeb1; apoptosis knee; mir 129 ... See more keywords

Low CPEB1 levels may predict the benefit of 5-fluorouracil treatment in patients with colon or stomach adenocarcinoma

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Published in 2022 at "Journal of Gastrointestinal Oncology"

DOI: 10.21037/jgo-22-561

Abstract: Background For patients with colon or stomach adenocarcinoma, 5-fluorouracil (5-FU) is an essential component of systemic chemotherapy in the palliative and adjuvant settings. The post-transcriptional regulatory factor cytoplasmic polyadenylation element-binding protein 1 (CPEB1) has been… read more here.

Keywords: patients colon; cpeb1; stomach adenocarcinoma; colon stomach ... See more keywords
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Obesity-Induced miR-455 Upregulation Promotes Adaptive Pancreatic β-cell Proliferation Through the CPEB1/CDKN1B Pathway.

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Published in 2022 at "Diabetes"

DOI: 10.2337/db21-0134

Abstract: Pancreatic β-cell adapt to compensate for increased metabolic demand during obesity. Although the microRNA (miRNA) pathway has an essential role in β-cell expansion, whether it is involved in adaptive proliferation is largely unknown. First, we… read more here.

Keywords: cell; cell proliferation; cpeb1; mir 455 ... See more keywords