Articles with "cpeb4" as a keyword



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PO-305 Depletion of CPEB4 in the metastatic niche enhances metastatic growth

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Published in 2018 at "ESMO Open"

DOI: 10.1136/esmoopen-2018-eacr25.818

Abstract: Introduction Metastasis is the primary cause of death in cancer patients. The implantation and growth of metastatic cells in secondary organs is dependent on both cell-intrinsic factors and microenvironmental (‘host’) factors. Host cells are activated… read more here.

Keywords: cpeb4; cell; metastatic niche; growth ... See more keywords
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CPEB4 Inhibit Cell Proliferation via Upregulating p21 mRNA Stability in Renal Cell Carcinoma

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Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.687253

Abstract: Cytoplasmic polyadenylation element-binding protein 4 (CPEB4) has been reported to be dysregulated in a variety of cancers and seems to play paradoxical roles in different cancers. However, the functional roles of CPEB4 in Renal cell… read more here.

Keywords: p21 mrna; renal cell; cell carcinoma; cpeb4 ... See more keywords
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CPEB4-Dependent Neonate-Born Granule Cells Are Required for Olfactory Discrimination

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Published in 2019 at "Frontiers in Behavioral Neuroscience"

DOI: 10.3389/fnbeh.2019.00005

Abstract: The rodent olfactory bulb (OB) contains two distinct populations of postnatally born interneurons, mainly granule cells (GCs), to support local circuits throughout life. During the early postnatal period (i.e., 2 weeks after birth), GCs are… read more here.

Keywords: cpeb4; neonate born; cpeb4 dependent; early postnatal ... See more keywords
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CPEB4-Promoted Paclitaxel Resistance in Ovarian Cancer In Vitro Relies on Translational Regulation of CSAG2

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Published in 2020 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2020.600994

Abstract: Background: Drug resistance is a major obstacle in chemotherapy for ovarian cancer, wherein the up regulation of drug-resistant genes plays an important role. The cytoplasmic polyadenylation element binding protein 4 (CPEB4) is an RNA binding… read more here.

Keywords: cpeb4; resistance ovarian; paclitaxel resistance; ovarian cancer ... See more keywords