Synergy Effects of HPV E6‐E7 Encoding mRNA and Nucleic Acid Immunostimulators Improve Therapeutic Potential in TC‐1 Graft Tumor
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Medical Virology"
DOI: 10.1002/jmv.70075
Abstract: Cervical cancer is the second most common cancer among women globally and the most prevalent cancer in developing countries, which was caused by human papillomavirus (HPV) infection. Messenger RNA (mRNA) vaccines have opened up new… read more here.
Keywords: nucleic acid; cancer; mrna; tumor ... See more keywords
Development of CpG-adjuvanted stable prefusion SARS-CoV-2 spike antigen as a subunit vaccine against COVID-19
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-77077-z
Abstract: The COVID-19 pandemic is a worldwide health emergency which calls for an unprecedented race for vaccines and treatment. In developing a COVID-19 vaccine, we applied technology previously used for MERS-CoV to produce a prefusion-stabilized SARS-CoV-2… read more here.
Keywords: prefusion; cpg 1018; cov spike; sars cov ... See more keywords
Overcoming Aging-Associated Poor Influenza Vaccine Responses with CpG 1018 Adjuvant
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DOI: 10.3390/vaccines10111894
Abstract: Aging is associated with diminished immune system function, which renders old people vulnerable to influenza infection and also less responsive to influenza vaccination. This study explored whether the CpG 1018 adjuvant was effective in enhancing… read more here.
Keywords: 1018 adjuvant; cpg 1018; antibody; pdm09 vaccine ... See more keywords
CpG 1018 Is an Effective Adjuvant for Influenza Nucleoprotein
Sign Up to like & getrecommendations! Published in 2023 at "Vaccines"
DOI: 10.3390/vaccines11030649
Abstract: Current influenza vaccines mainly induce neutralizing antibodies against the highly variable surface antigen hemagglutinin and require annual manufacturing and immunization. Different from surface antigens, intracellular nucleoprotein (NP) is highly conserved and has been an attractive… read more here.
Keywords: immunization; cpg 1018; effective adjuvant; influenza ... See more keywords