Induced Expression of Endogenous CXCR4 in iPSCs by Targeted CpG Demethylation Enhances Cell Migration Toward the Ligand CXCL12
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DOI: 10.1007/s10753-018-0869-5
Abstract: Poor homing of cells after transplantation is an unresolved common issue in cardiac cell therapies. To enhance stem cell homing, the ligand CXC motif chemokine 12 (CXCL12) and its specific receptor CXC receptor type 4… read more here.
Keywords: cpg demethylation; ipscs; migration; expression ... See more keywords
The Effect of Single CpG Demethylation on the Pattern of DNA-Protein Binding
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DOI: 10.3390/ijms20040914
Abstract: Epidermal differentiation is a complex process and its regulation may involve epigenetic factors. Analysis of DNA methylation in 20 selected regions within the epidermal differentiation complex (EDC) gene cluster by targeted next-generation sequencing (NGS) detected… read more here.
Keywords: cpg demethylation; dna; demethylation; single cpg ... See more keywords