Evaluating methylation of human ribosomal DNA at each CpG site reveals its utility for cancer detection using cell-free DNA
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac278
Abstract: Ribosomal deoxyribonucleic acid (DNA) (rDNA) repeats are tandemly located on five acrocentric chromosomes with up to hundreds of copies in the human genome. DNA methylation, the most well-studied epigenetic mechanism, has been characterized for most… read more here.
Keywords: methylation; rdna methylation; dna; cancer ... See more keywords
CpG site hypomethylation at ETS1-binding region regulates DLK1 expression in Chinese patients with Tetralogy of Fallot
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DOI: 10.3892/mmr.2022.12609
Abstract: Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart malformation accounting for ~10% of cases. Although the pathogenesis of TOF is complex and largely unknown, epigenetics plays a huge role, specifically DNA methylation.… read more here.
Keywords: expression; methylation; cpg site; tof ... See more keywords