The anticancer effect related to disturbances in redox balance on Caco-2 cells caused by an alkynyl gold(I) complex.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2016.11.009
Abstract: The alkynyl gold(I) derivative [Au(C≡CPh)(PTA)] (PTA=1,3,5-triaza-7-phosphaadamantane) induces apoptosis in colorectal carcinoma tumour cells (Caco-2) without affecting to normal enterocytes. [Au(C≡CPh)(PTA)] is a slight lipophilic drug, stable in PBS (Phosphate Buffered Saline) and able to bind… read more here.
Keywords: effect related; cph pta; anticancer effect; alkynyl gold ... See more keywords