Mutation and evolution of metallo-beta-lactamase CphA under the selective pressure of biapenem continuous concentration gradient.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2022.111776
Abstract: One of the resistance mechanisms of superbugs is to hydrolyze antibiotics by producing metallo-β-lactamases (MβLs). To verify how MβLs evolved to increase in activity in response to various β-lactam antibiotics, the mutation and evolution of… read more here.
Keywords: cpha; metallo; mutation evolution; binding pocket ... See more keywords
Cyanophycin Synthesis Optimizes Nitrogen Utilization in the Unicellular Cyanobacterium Synechocystis sp. Strain PCC 6803
Sign Up to like & getrecommendations! Published in 2018 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.01298-18
Abstract: We clarified the elusive biological function of cyanophycin in the nondiazotrophic cyanobacterium Synechocystis sp. PCC 6803. Cyanophycin is a dynamic carbon/nitrogen storage polymer (multi-arginyl-l-polyaspartate) that is conditionally present in most cyanobacteria and a few heterotrophic… read more here.
Keywords: nitrogen; cyanophycin; cyanophycin synthesis; cyanobacterium ... See more keywords