Sample sizes of prediction model studies in prostate cancer were rarely justified and often insufficient.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of clinical epidemiology"
DOI: 10.1016/j.jclinepi.2020.12.011
Abstract: OBJECTIVE Developing clinical prediction models (CPMs) on data of sufficient sample size is critical to help minimise overfitting. Using prostate cancer as a clinical exemplar, we aimed to investigate to what extent existing CPMs adhere… read more here.
Keywords: sample; cpms; prostate cancer; sample size ... See more keywords
Quantitative measurement of oxidative damage in erythrocytes as indicator in benzene intoxications
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2018.1455786
Abstract: Abstract The metabolism of aromatic hydrocarbons by the organism forms products that cause cell death depending on the type of exposure. Benzene exposure has been linked to oxidative stress, hepatic damage, aplastic anemia, and hematopoietic… read more here.
Keywords: cpms; benzene intoxications; oxidative damage; exposure ... See more keywords
Clinical prediction in defined populations: a simulation study investigating when and how to aggregate existing models
Sign Up to like & getrecommendations! Published in 2017 at "BMC Medical Research Methodology"
DOI: 10.1186/s12874-016-0277-1
Abstract: BackgroundClinical prediction models (CPMs) are increasingly deployed to support healthcare decisions but they are derived inconsistently, in part due to limited data. An emerging alternative is to aggregate existing CPMs developed for similar settings and… read more here.
Keywords: cpms; aggregation; defined populations; study ... See more keywords
A critical evaluation of the EU-virtual consultation platform (CPMS) within the European Reference Network on Rare Endocrine Conditions
Sign Up to like & getrecommendations! Published in 2022 at "Endocrine Connections"
DOI: 10.1530/ec-22-0281
Abstract: In 2017, the European Commission installed 24 European Reference Networks (ERNs) for different categories of rare and complex conditions to facilitate cross-border health care via virtual case consultations in a secure Clinical Patient Management System… read more here.
Keywords: european reference; system; evaluation; network ... See more keywords
Clinical prediction models of fractional flow reserve: an exploration of the current evidence and appraisal of model performance.
Sign Up to like & getrecommendations! Published in 2021 at "Quantitative imaging in medicine and surgery"
DOI: 10.21037/qims-20-1274
Abstract: Background Invasive fractional flow reserve (FFR) is a standard indicator of coronary stenoses' hemodynamic severity. Clinical prediction models (CPMs) may help differentiate ischemic from non-ischemic lesions without using a pressure wire but by integrating related… read more here.
Keywords: flow reserve; fractional flow; prediction models; clinical prediction ... See more keywords