Targeting MET Signalling Activated by CPNE3‐RACK1 Interaction Through VWFA Domain to Suppress Lung Cancer Progression
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.70926
Abstract: Despite advances in diagnosis and treatment, the prognosis of non‐small cell lung cancer (NSCLC) remains poor. Therefore, it is urgent to identify potential molecular targets. In this study, we investigated the function and internal mechanism… read more here.
Keywords: rack1; lung cancer; vwfa domain; cpne3 ... See more keywords
SQSTM1/P62 Mediates the Effects of CPNE3 on the Epithelialmesenchymal Transition and Migratory Inhibition of Lung Adenocarcinoma Cells.
Sign Up to like & getrecommendations! Published in 2025 at "Current medicinal chemistry"
DOI: 10.2174/0109298673340242250102104725
Abstract: INTRODUCTION Copine-3 (CPNE3) is a conservative calcium-dependent phospholipid-binding protein belonging to the copines protein family. CPNE3 has been implicated in the development and progression of several diseases, including cancer. METHOD Herein, we investigated the molecular… read more here.
Keywords: sqstm1 p62; transition; cpne3; lung adenocarcinoma ... See more keywords
CPNE3 promotes migration and invasion in non-small cell lung cancer by interacting with RACK1 via FAK signaling activation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cancer"
DOI: 10.7150/jca.25872
Abstract: Approximately 90% of patients diagnosed with non-small cell lung cancer (NSCLC) die due to distant metastases. However, the complicated molecular and cellular mechanisms involved in lung cancer metastasis remain poorly understood. Copine III (CPNE3), a… read more here.
Keywords: cpne3; lung cancer; non small; cancer ... See more keywords