Calcium pyrophosphate deposition disease: a frequent finding in patients with long-standing erosive gout
Sign Up to like & getrecommendations! Published in 2018 at "Scandinavian Journal of Rheumatology"
DOI: 10.1080/03009742.2017.1332239
Abstract: Objective: To characterize patients with both monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals in their synovial fluid (SF). Method: Forty-nine gout patients with acute arthritis were included. Those patients with MSU crystals only in… read more here.
Keywords: disease; deposition; cpp crystals; gout ... See more keywords
Regulation of crystal induced inflammation: current understandings and clinical implications
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2021.1937129
Abstract: ABSTRACT Introduction: Accumulation of abnormal crystals in the body, derived from endogenous or exogenous materials can drive a wide spectrum of inflammatory disease states. It is well established that intra-articular deposition of monosodium urate (MSU)… read more here.
Keywords: crystal induced; regulation crystal; cpp crystals; induced inflammation ... See more keywords
THU0034 The inflammatory potential of calcium pyrophosphate crystals depends on their capacity to induce nf-κb and mapk pathways
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.4741
Abstract: Background Calcium pyrophosphate (CPP) crystal-induced inflammation is mainly driven by interleukin (IL)-1β. IL-1β production involves a two-step process including the formation of pro-IL-1β through NF-κB activation and its maturation inti active IL-1β through NLRP3 inflammasome… read more here.
Keywords: cpp crystals; calcium pyrophosphate; production; mapk ... See more keywords