Impaired Dynamic Sarcoplasmic Reticulum Ca Buffering in Autosomal Dominant CPVT2
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DOI: 10.1161/circresaha.121.320661
Abstract: Background: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a potentially lethal cardiac arrhythmia syndrome triggered by catecholamines released during exercise, stress, or sudden emotion. Variants in the calsequestrin-2 gene (CASQ2), encoding the major calcium (Ca) binding… read more here.
Keywords: dominant cpvt2; sarcoplasmic reticulum; cpvt2; autosomal dominant ... See more keywords