Cross-priming induces immunodomination in the presence of viral MHC class I inhibition
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DOI: 10.1371/journal.ppat.1006883
Abstract: Viruses have evolved mechanisms of MHCI inhibition in order to evade recognition by cytotoxic CD8+ T cells (CTLs), which is well-illustrated by our prior studies on cowpox virus (CPXV) that encodes potent MHCI inhibitors. Deletion… read more here.
Keywords: cpxv; immunodomination; inhibition; mhci ... See more keywords
Genomic Sequencing and Phylogenomics of Cowpox Virus
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DOI: 10.3390/v14102134
Abstract: Cowpox virus (CPXV; genus Orthopoxvirus; family Poxviridae) is the causative agent of cowpox, a self-limiting zoonotic infection. CPXV is endemic in Eurasia, and human CPXV infections are associated with exposure to infected animals. In the… read more here.
Keywords: cowpox virus; sequencing phylogenomics; cpxv; genomic sequencing ... See more keywords